Tos-PEG9-t-butyl ester manufacturers
- Tos-PEG9-COOtBu
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2025-06-07
- CAS:1345337-28-1
- Min. Order: 1g
- Purity: >96.00%
- Supply Ability: 1g
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| | Tos-PEG9-t-butyl ester Basic information |
| Product Name: | Tos-PEG9-t-butyl ester | | Synonyms: | Tos-PEG8-CH2CH2COOtBu;Tos-PEG9-t-butyl ester;Tos-PEG9-Boc;4,7,10,13,16,19,22,25-Octaoxaheptacosanoic acid, 27-[[(4-methylphenyl)sulfonyl]oxy]-, 1,1-dimethylethyl ester;Tos-PEG8-CH2CH2COOtBu/4,7,10,13,16,19,22,25-Octaoxaheptacosanoic acid, 27-[[(4-methylphenyl)sulfonyl]oxy]-, 1,1-dimethylethyl ester;tert-butyl 1-(tosyloxy)-3,6,9,12,15,18,21,24-octaoxaheptacosan-27-oate | | CAS: | 1345337-28-1 | | MF: | C30H52O13S | | MW: | 652.79 | | EINECS: | | | Product Categories: | | | Mol File: | 1345337-28-1.mol |  |
| | Tos-PEG9-t-butyl ester Chemical Properties |
| Boiling point | 677.8±55.0 °C(Predicted) | | density | 1.142±0.06 g/cm3(Predicted) | | storage temp. | Store at Room Tem. | | solubility | Soluble in DMSO, DCM, DMF |
| | Tos-PEG9-t-butyl ester Usage And Synthesis |
| Description | Tos-PEG9-t-butyl ester is a PEG linker containing a t-butyl ester and a tosyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The tosyl group is a very good leaving group for nucleophilic substitution reactions. | | Uses | Tos-PEG9-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | | IC 50 | PEGs; Alkyl/ether | | References | [1] Snaebjornsson MT, et al. Non-canonical functions of enzymes facilitate cross-talk between cell metabolic and regulatory pathways. Exp Mol Med. 2018 Apr 16;50(4):34. DOI:10.1038/s12276-018-0065-6 |
| | Tos-PEG9-t-butyl ester Preparation Products And Raw materials |
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