Α-金环蛇毒
| 中文名称 | Α-金环蛇毒 |
|---|---|
| 中文同义词 | Α-金环蛇毒;ALPHA-银环蛇神经毒素;H-ILE-VAL-CYS-HIS-THR-THR-ALA-THR-SER-PRO-ILE-SER-ALA-VAL-THR-CYS-PRO-PRO-GLY-GLU-ASN-LEU-CYS-TYR-ARG-LYS-MET-TRP-CYS-ASP-ALA-PHE-CYS-SER-SER-ARG-GLY-LYS-VAL-VAL-GLU-LEU-GLY-CYS-ALA-ALA-THR-CYS-PRO-SER-LYS-LYS-PRO-TYR-GLU-GLU-VAL-THR-CYS-CYS-SER-THR-ASP-LYS-CYS-ASN-PRO-HIS-PRO-LYS-GLN-ARG-PRO-GLY-OH;Α-真菌毒素;Α-金环蛇毒素;Α-银环蛇神经毒素;Α-银环蛇毒素;化合物 Α-BUNGAROTOXIN |
| 英文名称 | ALPHA-BUNGAROTOXIN |
| 英文同义词 | ALPHA-BUNGAROTOXIN;ALPHA-BUNGAROTOXIN, BUNGARUS MULTICINCTUS;ALPHA-BUTX;ALPHA-BGT;A-BUNGAROTOXIN;M.W. 7984.14 C338H529N97O105S11;H-ILE-VAL-CYS-HIS-THR-THR-ALA-THR-SER-PRO-ILE-SER-ALA-VAL-THR-CYS-PRO-PRO-GLY-GLU-ASN-LEU-CYS-TYR-ARG-LYS-MET-TRP-CYS-ASP-ALA-PHE-CYS-SER-SER-ARG-GLY-LYS-VAL-VAL-GLU-LEU-GLY-CYS-ALA-ALA-THR-CYS-PRO-SER-LYS-LYS-PRO-TYR-GLU-GLU-VAL-THR-CYS-CYS-SER-THR-ASP-LYS-CYS-ASN-PRO-HIS-PRO-LYS-GLN-ARG-PRO-GLY-OH;BUNGARUS MULTICINCTUS TOXIN, ALPHA |
| CAS号 | 11032-79-4 |
| 分子式 | C50H70O14 |
| 分子量 | 895.0824 |
| EINECS号 | 234-266-6 |
| 相关类别 | Acetylcholine receptor |
| Mol文件 | 11032-79-4.mol |
| 结构式 |  |
Α-金环蛇毒 性质
| 储存条件 | −20°C |
|---|---|
| 溶解度 | 溶于无菌水 |
| 形态 | 固体 |
| 颜色 | 白色 |
| 水溶解性 | Soluble in water |
| 序列 | Ile-Val-Cys-His-Thr-Thr-Ala-Thr-Ser-Pro-Ile-Ser-Ala-Val-Thr-Cys-Pro-Pro-Gly-Glu-Asn-Leu-Cys-Tyr-Arg-Lys-Met-Trp-Cys-Asp-Ala-Phe-Cys-Ser-Ser-Arg-Gly-Lys-Val-Val-Glu-Leu-Gly-Cys-Ala-Ala-Thr-Cys-Pro-Ser-Lys-Lys-Pro-Tyr-Glu-Glu-Val-Thr-Cys-Cys-Ser-Thr-Asp-Lys-Cys-Asn-Pro-His-Pro-Lys-Gln-Arg-Pro-Gly (Disulfide bridge: Cys3-Cys23;Cys16-Cys44;Cys29-Cys33;Cys48-Cys59;Cys60-Cys65) |
| InChIKey | LYTCVQQGCSNFJU-UHFFFAOYSA-N |
| CAS 数据库 | 11032-79-4 |
α-Bungarotoxin 是烟碱乙酰胆碱受体 (nAChRs) 的竞争性拮抗剂。α-Bungarotoxin 是一种选择性 α7 受体 (α7 receptor) 阻滞剂，IC50 为 1.6 nM。
α-Bungarotoxin binds specifically and with high affinity to the nicotinic acetylcholine receptor and competes with binding of the natural ligand. α-Bungarotoxin (α-BTX), is a potent competitive inhibitors of nicotinic acetylcholine receptor function and is highly toxic due to functional blockade of AcChoRs at the neuromuscular junction.
安全信息
| WGK Germany | 3 |
|---|---|
| RTECS号 | QQ4495249 |
| 存储类别 | 11 - 可燃固体 |
| 毒性 | chicken,LD50,intramuscular,74ug/kg (0.074mg/kg),Toxicon. Vol. 7, Pg. 89, 1969. |
| 提供商 | 语言 |
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英文
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