- 3,5-Dibromopyridine
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- $8.90 / 1KG
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2025-10-21
- CAS:625-92-3
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 10 mt
- 3,5-Dibromopyridine
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- $200.00 / 1KG
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2025-09-25
- CAS:625-92-3
- Min. Order: 1KG
- Purity: 99%, 99.5% Sublimated
- Supply Ability: g-kg-tons, free sample is available
- 3,5-Dibromopyridine
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- $0.00 / 25KG
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2025-08-19
- CAS:625-92-3
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 50000KG/month
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| | 3,5-Dibromopyridine Basic information |
| Product Name: | 3,5-Dibromopyridine | | Synonyms: | 3,5-DIBROMOPYRIDINE;IFLAB-BB F1995-0190;3,5-Dibromopyridine,99%;3,5-Dibromopyridine, 98+%;3,5-dibormopyridine;3,5-DibroMopyridine, 97+%;3, 5-2 broMide pyridine;3,5-Dibromopyridine 99% | | CAS: | 625-92-3 | | MF: | C5H3Br2N | | MW: | 236.89 | | EINECS: | 210-916-4 | | Product Categories: | Halogenated Heterocycles;Heterocyclic Building Blocks;C5Heterocyclic Building Blocks;Brominated heterocyclic series;Boronate Ester;Boronic Acid;Potassium Trifluoroborate;Pyridines derivates;API intermediates;Halogenated;Organohalides;Aromatics Compounds;Bromopyridines;Halopyridines;Aromatics;Bases & Related Reagents;Nucleotides;blocks;Bromides;Pyridines;Pyridine;Pyridines, Pyrimidines, Purines and Pteredines;bc0001;1;625-92-3 | | Mol File: | 625-92-3.mol |  |
| | 3,5-Dibromopyridine Chemical Properties |
| Melting point | 110-115 °C (lit.) | | Boiling point | 222 °C | | density | 2.0383 (rough estimate) | | refractive index | 1.5800 (estimate) | | storage temp. | Inert atmosphere,Room Temperature | | solubility | DMSO (Slightly, Heated), Methanol (Slightly) | | pka | 0.52±0.20(Predicted) | | form | Needle-Like Crystals | | color | White to light beige | | Water Solubility | Soluble in Chloroform and Methanol. Insoluble in water. | | BRN | 108477 | | InChIKey | SOSPMXMEOFGPIM-UHFFFAOYSA-N | | CAS DataBase Reference | 625-92-3(CAS DataBase Reference) | | NIST Chemistry Reference | 3,5-Dibromopyridine(625-92-3) | | EPA Substance Registry System | 3,5-Dibromopyridine (625-92-3) |
| | 3,5-Dibromopyridine Usage And Synthesis |
| Chemical Properties | Light-Yellow Solid | | Uses | 3-Acetylamino-5-ethoxypyridine was prepared by converting 3, 5-dibromopyridine with sodium ethylate into 3-bromo-5-ethoxypyridine, allowing this substance to interact with ammonia and acetylating the aminoethoxypyridine thus formed with acetic anhydride. Lithiation of 3, 5-dibromopyridine with LDA and subsequent reaction with electrophiles provided 4-alkyl-3, 5-dibromopyridines 2 in high yield. Ligand was prepared by a Pd(0)-catalyzed cross-coupling reaction of 3,5-dibromopyridine and 5-tributylstannyl-3,3?-bipyridine. The synthesis of 3, 5-bis (2-indolyl) pyridine and 3-[(2-indolyl)-5-phenyl] pyridine derivatives as includes Stille or Suzuki type reactions, which were realized on the 3,5-dibromopyridine. | | Definition | ChEBI: 3,5-dibromopyridine is a dibromopyridine. | | Application | 3,5-Dibromopyridine (3,5-DBP) can be used for:
(1) Spectroscopic analysis: FTIR and FT Raman spectra in the solid phase of 3,5-DBP and 3,5- dichloro-2,4,6-trifluoropyridine (3,5-DCTFP) were recorded in the regions of 4000-400 cm-1 and 3500-100 cm-1, respectively[1].
(2) Chemical reactions: 3,5-DBP can be reacted with phenyl isocyanate. chemoselective Staudinger-Phosphite reaction of 2,4,6-triazido-3,5-dibromopyridine azide moiety[2-3].
(3) Organic synthesis: Using 3,5-dibromopyridine as raw material can be used to prepare 3-acetamido-5-ethoxypyridine[4]. | | General Description | 3,5-Dibromopyridine undergoes lithiation with lithium diisopropylamide and on subsequent reaction with electrophiles yields 4-alkyl-3,5-dibromopyridines. | | References | [1] V. KRISHNAKUMAR R. J X. Density functional theory calculations and vibrational spectra of 3,5-dibromopyridine and 3,5-dichloro-2,4,6-trifluoropyridine[J]. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2005. DOI:10.1016/j.saa.2004.03.038.
[2] SERGEI V. CHAPYSHEV Igor K Y Alexander V Chernyak. Chemoselective Staudinger-Phosphite Reaction on the Azido Groups of 2,4,6-Triazido-3,5-dibromopyridine[J]. Journal of Heterocyclic Chemistry, 2015. DOI:10.1002/jhet.2339.
[3] T. HISANO M. I Toshikazu Matsuoka. THE REACTION OF 3,5-DIBROMOPYRIDINE N-OXIDE WITH PHENYL ISOCYANATE[J]. ChemInform, 1974. DOI:10.1002/CHIN.197448358.
[4] H. J. HERTOG A. V D L A W M Falter. The reactivity of bromine atoms in brominated pyridines. The preparation of 3-acetylamino-5-ethoxypyridine from 3,5-dibromopyridine?[J]. Recueil des Travaux Chimiques des Pays-Bas, 1948. DOI:10.1002/RECL.19480670507. |
| | 3,5-Dibromopyridine Preparation Products And Raw materials |
| Preparation Products | 5-methoxypyridin-3-amine-->5-Bromo-2-fluoro-3-methoxypyridine-->3-Amino-5-hydroxypyridine-->5-(BENZYLOXY)PYRIDIN-3-AMINE-->5-METHOXY-PYRIDINE-3-CARBALDEHYDE-->3-(BENZYLOXY)-5-BROMOPYRIDINE-->5-Bromopyridine-3-boronic acid-->3-Bromo-5-fluoropyridine-->3-Amino-5-bromopyridine-->3-BROMO-5-(METHYLTHIO)PYRIDINE-->2-(5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)pyridin-3-yl)propan-2-ol-->4,6-Di(4-carboxyphenyl)pyrimidine-->3-BroMo-5-(prop-1-en-2-yl)pyridine-->3,5-Difluoro-4-pyridinecarboxaldehyde-->3,5-Dibromo-4-cyanopyridine, 97%-->3,5-DIBROMOPYRIDINE 1-OXIDE-->5-BROMO-3-METHOXY-2-NITROPYRIDINE-->3,5-Dimethoxypyridine |
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