- Baccatin III
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- $44.00
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2026-07-31
- CAS:27548-93-2
- Purity: 99.47%
- Supply Ability: 10g
- Baccatin III
-
-
2023-02-24
- CAS:27548-93-2
- Min. Order: 20mg
- Purity: ≥98%(HPLC)
- Supply Ability: 10 g
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| | Baccatine III Basic information |
| Product Name: | Baccatine III | | Synonyms: | BACCATINE III;BACCATIN III;(1S)-4α,10β-Bis(acetoxy)-2α-(benzoyloxy)-5β,20-epoxy-1,7β,13α-trihydroxytaxa-11-ene-9-one;(2aR)-6α,12bβ-Bisacetoxy-12β-(benzoyloxy)-1,2aβ,3,4,4a,6,9,10,11,12,12aβ,12b-dodecahydro-4α,9β,11β-trihydroxy-4aα,8,13,13-tetramethyl-7,11-methano-5H-cyclodeca[3,4]benzo[1,2-b]oxete-5-one;(2aR)-6α,12bβ-Diacetoxy-12β-benzoyloxy-1,2aβ,3,4,4a,6,9,10,11,12,12aβ,12b-dodecahydro-4α,9β,11β-trihydroxy-4aα,8,13,13-tetramethyl-7,11α-methano-5H-cyclodeca[3,4]benzo[1,2-b]oxete-5-one;6α,12bβ-Diacetoxy-12β-benzoyloxy-1,2aβ,3,4,4a,6,9,10,11,12,12aβ,12b-dodecahydro-4α,9β,11β-trihydroxy-4aα,8,13,13-tetramethyl-7,11α-methano-5H-cyclodeca[3,4]benzo[1,2-b]oxete-5-one;Baccatine III,95%;BACCATIN III 98% | | CAS: | 27548-93-2 | | MF: | C31H38O11 | | MW: | 586.63 | | EINECS: | | | Product Categories: | Inhibitors;API;Intermediates & Fine Chemicals;Pharmaceuticals;Aromatics;Chiral Reagents;Heterocycles | | Mol File: | 27548-93-2.mol |  |
| | Baccatine III Chemical Properties |
| Melting point | 229-234 °C | | Boiling point | 562.81°C (rough estimate) | | density | 1.2062 (rough estimate) | | refractive index | 1.5455-1.5475 | | storage temp. | Sealed in dry,Store in freezer, under -20°C | | solubility | DMSO : 125 mg/mL (213.08 mM; Need ultrasonic) | | form | Solid | | pka | 12.76±0.70(Predicted) | | color | White to off-white | | Water Solubility | insoluble | | Stability: | 4 Year Shelf Life | | InChIKey | OVMSOCFBDVBLFW-VHLOTGQHSA-N | | SMILES | O1C[C@@]2(OC(C)=O)[C@@]3([H])[C@H](OC(=O)C4=CC=CC=C4)[C@@]4(O)C(C)(C)C(=C(C)[C@@H](O)C4)[C@@H](OC(C)=O)C(=O)[C@]3(C)[C@@H](O)C[C@@]12[H] | | CAS DataBase Reference | 27548-93-2 |
| Hazard Codes | T | | Risk Statements | 45-46-22-36/37/38-48/20/22 | | Safety Statements | 53-22-26-36/37/39-45-24/25 | | RIDADR | 1544 | | WGK Germany | 3 | | HazardClass | 6.1(b) | | PackingGroup | III | | HS Code | 29329990 | | Storage Class | 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects | | Hazard Classifications | Carc. 1B
Eye Irrit. 2
Muta. 1B
Skin Irrit. 2
STOT SE 3 |
| | Baccatine III Usage And Synthesis |
| Chemical Properties | White to Off-White Powder | | Uses | A precursor to Paclitaxel, a neoplasm inhibitor to ovarian and breast cancers found in Taxus species | | Uses | immunomodulator, induces apoptosis | | Definition | ChEBI: A tetracyclic diterpenoid isolated from plant species of the genus Taxus. | | in vivo | Baccatin III (0.05-0.5 mg/kg; intragastrically; once daily; 17-19 days) significantly inhibits tumor growth and reduced accumulation of myeloid-derived suppressor cells (MDSCs) in BALB/c mice with 4T1 breast cancer or CT26 colon cancer[1].
Baccatin III (5-10 mg/kg; intraperitoneally; single; 21 days) alleviates Bleomycin (HY-108345)-induced lung fibrosis in C57BL/6 mice by inhibiting TGF-β1[2]. |
| | Baccatine III Preparation Products And Raw materials |
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