| Company Name: |
Wuhan Chemwish Technology Co., Ltd
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| Tel: |
86-027-67849912 |
| Email: |
sales@chemwish.com |
| Products Intro: |
Product Name:FMoc-(R)-2-aMino-3-hydroxy-3-Methylbutanoic acid
Package:500Mg;1g;5g;25g;100g
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| Company Name: |
SINO High Goal Chemical Technology Co., Ltd.
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| Tel: |
021-57646680 18306277365 |
| Email: |
sunkai@chembiobanksh.com |
| Products Intro: |
Product Name:FMOC-(R)-2-AMINO-3-HYDROXY-3-METHYLBUTANOIC ACID
CAS:884880-39-1
Purity:99% Package:5g;10g;15g;25g; Remarks:500
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| Company Name: |
Shanghai GL Peptide Ltd.
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| Tel: |
+86-21-61263340; 17609490614 13764994101 |
| Email: |
fisherwang@glschina.com |
| Products Intro: |
Product Name:(2R)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-hydroxy-3-methylbutanoic acid
CAS:884880-39-1
Purity:95%;98%;99% Package:0.1g, 0.25g, 1g, 5g, 10g, 25g, 50g, 100g
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| | FMOC-(R)-2-AMINO-3-HYDROXY-3-METHYLBUTANOIC ACID Basic information |
| Product Name: | FMOC-(R)-2-AMINO-3-HYDROXY-3-METHYLBUTANOIC ACID | | Synonyms: | FMOC-(R)-2-AMINO-3-HYDROXY-3-METHYLBUTANOIC ACID;(R)-Fmoc-b,b-dimethyl-serine;(R)-Fmoc-β-hydroxy-valine≥ 99% (HPLC);(2R)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-hydroxy-3-methylbutanoic acid;D-Valine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-3-hydroxy-;N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-hydroxy-D-valine;(R)-N-Fmoc-β-Hydroxyvaline;Fmoc-3-Methyl-D-threonine | | CAS: | 884880-39-1 | | MF: | C20H21NO5 | | MW: | 355.38 | | EINECS: | | | Product Categories: | unnatural amino acids | | Mol File: | Mol File |  |
| | FMOC-(R)-2-AMINO-3-HYDROXY-3-METHYLBUTANOIC ACID Chemical Properties |
| storage temp. | 2-8°C | | Appearance | White to off-white Solid | | Optical Rotation | 7.433°(C=0.504g/100mL, CHCL3, 20°C, 589nm) |
| | FMOC-(R)-2-AMINO-3-HYDROXY-3-METHYLBUTANOIC ACID Usage And Synthesis |
| Chemical Properties | White powder | | Synthesis | GENERAL STEPS: (R)-N-Fmoc-2-amino-3-hydroxy-3-methylbutanoic acid was synthesized in the following steps: first, (R)-2-((tert-butoxycarbonyl)amino)-3-hydroxy-3-methylbutanoic acid was stripped of the Boc protecting group in a 1:1 trifluoroacetic acid/dichloromethane solution. Subsequently, the Fmoc protection reaction was carried out using 9-fluorenylmethyl-N-succinimidyl carbonate (Fmoc-OSu) and sodium bicarbonate (NaHCO3) in aqueous acetone solution. After completion of the reaction, the product was purified by silica gel column chromatography (eluent ratio of 1:1:98 methanol/acetic acid/chloroform). Finally, the purified product was freeze-dried from aqueous acetonitrile solution to afford the target compound in 78% yield. | | References | [1] Patent: US2009/48161, 2009, A1. Location in patent: Page/Page column 40 |
| | FMOC-(R)-2-AMINO-3-HYDROXY-3-METHYLBUTANOIC ACID Preparation Products And Raw materials |
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