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| | PROTAC MDM2 Degrader-3 Basic information |
| Product Name: | PROTAC MDM2 Degrader-3 | | Synonyms: | PROTAC MDM2 Degrader-3;1-Piperazineacetic acid, 4-[[(4R,5S)-4,5-bis(4-chlorophenyl)-4,5-dihydro-2-[4-methoxy-2-(1-methylethoxy)phenyl]-1H-imidazol-1-yl]carbonyl]-2-oxo-, 1,1'-[oxybis(2,1-ethanediyloxy-2,1-ethanediyl)] ester, rel- | | CAS: | 2249750-23-8 | | MF: | C72H78Cl4N8O15 | | MW: | 1437.25 | | EINECS: | | | Product Categories: | PROTACs | | Mol File: | 2249750-23-8.mol |  |
| | PROTAC MDM2 Degrader-3 Chemical Properties |
| density | 1.37±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO: 10 mg/mL (6.96 mM) | | form | Solid | | pka | 3.16±0.70(Predicted) | | color | White to off-white |
| | PROTAC MDM2 Degrader-3 Usage And Synthesis |
| Uses | PROTAC MDM2 Degrader-3 is a MDM2 degrader based on PROTAC technology. PROTAC MDM2 Degrader-3 composes of a potent MDM2 inhibitor, linker, and the MDM2 ligand for E3 ubiquitin ligase[1]. | | IC 50 | MDM2 | | References | [1] Method of inducing of self-degradation of MDM2 using E3 ubiquitin ligase dimer amide small molecule PROTACs. CN108610333A. |
| | PROTAC MDM2 Degrader-3 Preparation Products And Raw materials |
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