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| | PROTAC MDM2 Degrader-2 Basic information |
| Product Name: | PROTAC MDM2 Degrader-2 | | Synonyms: | PROTAC MDM2 Degrader-2;1-Piperazineacetamide, N,N'-[1,2-ethanediylbis(oxy-2,1-ethanediyl)]bis[4-[[(4R,5S)-4,5-bis(4-chlorophenyl)-4,5-dihydro-2-[4-methoxy-2-(1-methylethoxy)phenyl]-1H-imidazol-1-yl]carbonyl]-2-oxo-, rel- | | CAS: | 2249944-99-6 | | MF: | C70H76Cl4N10O12 | | MW: | 1391.23 | | EINECS: | | | Product Categories: | | | Mol File: | 2249944-99-6.mol |  |
| | PROTAC MDM2 Degrader-2 Chemical Properties |
| density | 1.38±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO: 50 mg/mL (35.94 mM) | | pka | 14.02±0.46(Predicted) | | form | Solid | | color | Off-white to light yellow |
| | PROTAC MDM2 Degrader-2 Usage And Synthesis |
| Uses | PROTAC MDM2 Degrader-2 is a MDM2 degrader based on PROTAC technology. PROTAC MDM2 Degrader-2 composes of a potent MDM2 inhibitor, linker, and the MDM2 ligand for E3 ubiquitin ligase (CN108610333A)[1]. | | IC 50 | MDM2 | | References | [1] Method of inducing of self-degradation of MDM2 using E3 ubiquitin ligase dimer amide small molecule PROTACs. CN108610333A. |
| | PROTAC MDM2 Degrader-2 Preparation Products And Raw materials |
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