PS 423 manufacturers
- PS423
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- $589.00
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2026-07-27
- CAS:1221964-37-9
- Purity: 99.26%
- Supply Ability: 10g
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| Product Name: | PS 423 | | Synonyms: | PS 423;Propanedioic acid, 2-[3-oxo-1-phenyl-3-[4-(trifluoromethyl)phenyl]propyl]-, 1,3-bis[(acetyloxy)methyl] ester;PS 210 AM;PS210AM;PS210-AM | | CAS: | 1221964-37-9 | | MF: | C25H23F3O9 | | MW: | 524.44 | | EINECS: | | | Product Categories: | | | Mol File: | 1221964-37-9.mol |  |
| | PS 423 Chemical Properties |
| Boiling point | 614.8±55.0 °C(Predicted) | | density | 1.326±0.06 g/cm3(Predicted) | | pka | 9.84±0.59(Predicted) | | form | Solid | | color | White to off-white |
| | PS 423 Usage And Synthesis |
| Uses | PS423 is a prodrug of PS210, acting as a substrate-selective inhibitor of PDK1, inhibiting the phosphorylation and activation of S6K. PS210 is a potent and selective PDK1 activator targeting the PIF binding pocket of PDK1[1]. | | References | [1] Busschots K, et al. Substrate-selective inhibition of protein kinase PDK1 by small compounds that bind to the PIF-pocket allosteric docking site. Chem Biol. 2012 Sep 21;19(9):1152-63. DOI:10.1016/j.chembiol.2012.07.017 |
| | PS 423 Preparation Products And Raw materials |
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