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| | Cephaeline hydrochloride Basic information |
| Product Name: | Cephaeline hydrochloride | | Synonyms: | CEPHAELINE HYDROCHLORIDE USP/EP/BP;Cephaeline hydrochloride,virus,Influenza Virus,Zika,alkaloid,Filovirus,Cephaeline,Ebola,Inhibitor,phenolic,inhibit,NSC 32944 monohydrochloride;Cephaeline hydrochloride, 10 mM in DMSO;Cephaeline hydrochloride | | CAS: | 3738-70-3 | | MF: | C28H40Cl2N2O4 | | MW: | 539.53 | | EINECS: | | | Product Categories: | | | Mol File: | 3738-70-3.mol |  |
| | Cephaeline hydrochloride Chemical Properties |
| | Cephaeline hydrochloride Usage And Synthesis |
| Uses | Cephaeline hydrochloride ((-)-Cephaeline hydrochloride) is a phenolic alkaloid in Indian Ipecac roots. Cephaeline hydrochloride exhibits potent inhibition of both Zika virus (ZIKV) and Ebola virus (EBOV) infections[1][2]. | | IC 50 | EBOV | | References | [1] N.P.Sahu, et al. Determination of emetine and cephaeline in Ipecac roots by high- performance liquid chromatography. Journal of Chromatography A. 1982 Apr; 238( 2):525-529.
[2] Yang S, et al. Emetine inhibits Zika and Ebola virus infections through two molecular mechanisms: inhibiting viral replication and decreasing viral entry. Cell Discov. 2018 Jun 5;4:31. DOI:10.1038/s41421-018-0034-1 |
| | Cephaeline hydrochloride Preparation Products And Raw materials |
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