- Pulchinenoside C
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- $29.00
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2026-06-11
- CAS:129741-57-7
- Purity: 99.83%
- Supply Ability: 10g
- Anemoside B4
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2023-02-24
- CAS:129741-57-7
- Min. Order: 5mg
- Purity: ≥98%(HPLC)
- Supply Ability: 10 g
- Pulchinenoside B4
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- $75.00
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2023-02-13
- CAS:129741-57-7
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 100MT
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| | PULCHINENOSIDE B4 Basic information |
| | PULCHINENOSIDE B4 Chemical Properties |
| Melting point | 208-215℃ | | density | 1.48 | | solubility | DMSO : 125 mg/mL (102.34 mM; Need ultrasonic) | | form | Powder | | pka | 12.50±0.70(Predicted) | | color | White to light yellow | | Major Application | pharmaceutical | | InChIKey | OUHBKBTZUPLIIA-UFEMLMIJNA-N |
| | PULCHINENOSIDE B4 Usage And Synthesis |
| Description | Pulchinenoside B4 is a triterpenoid glycoside that has been found in P. chinensis and has diverse biological activities. It inhibits cisplatin-induced apoptosis, increases in reactive oxygen species (ROS) production, and decreases in superoxide dismutase (SOD) and catalase activities in HEK293 cells when used at concentrations of 6 and 12 μM. Pulchinenoside B4 (50 and 100 mg/kg twice per day) prevents increases in plasma blood urea nitrogen (BUN) and creatinine levels, markers of kidney injury, in a mouse model of cisplatin-induced nephrotoxicity. It prevents xylene-induced ear edema in mice in a dose-dependent manner. Pulchinenoside B4 (50 mg/kg) inhibits LPS-induced increases in serum TNF-α, IL-6, and IL-1β levels a mouse model of LPS-induced systemic inflammation. | | Chemical Properties | White crystalline powder, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from the dried roots of Pulsatilla chinensis (Bge.) Regel. | | Uses | Pulchinenoside C is a triterpenoid saponin extract which acts as a minor molluscicidal agent in addition to tumor necrosis factor-α secretion inhibition. Anti-inflammatory. | | References | [1] HE LUAN . Anemoside B4 attenuates nephrotoxicity of cisplatin without reducing anti-tumor activity of cisplatin[J]. Phytomedicine, 2019, 56: Pages 136-146. DOI: 10.1016/j.phymed.2018.10.035
[2] NAIXIN KANG . Anti-inflammatory and immune-modulatory properties of anemoside B4 isolated from Pulsatilla chinensis in vivo[J]. Phytomedicine, 2019, 64: Article 152934. DOI: 10.1016/j.phymed.2019.152934 |
| | PULCHINENOSIDE B4 Preparation Products And Raw materials |
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