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ChemStrong Scientific Co.,Ltd
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0755-0755-66853366 13670046396 |
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| Products Intro: |
Product Name:16,16-dimethyl Prostaglandin E1
CAS:41692-15-3
Purity:95% HPLC Package:10mg;25mg;50mg;100mg
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| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
4008200310 |
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marketing@tsbiochem.com |
| Products Intro: |
Product Name:16,16-dimethyl Prostaglandin E1
CAS:41692-15-3
Package:1mg/RMB 1270;10mg/RMB 9860;5mg/RMB 5670
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| | 16,16-DIMETHYL PROSTAGLANDIN E1 Basic information |
| Product Name: | 16,16-DIMETHYL PROSTAGLANDIN E1 | | Synonyms: | 9-OXO-11ALPHA,15R-DIHYDROXY-16,16-DIMETHYL-PROST-13E-EN-1-OIC ACID;16,16-dimethylprostaglandin E;Prost-13-en-1-oic acid, 11,15-dihydroxy-16,16-dimethyl-9-oxo-, (11alpha,13E,15R)-;RQOFITYRYPQNLL-ZWSAOQBFSA-N;16,16-dimethyl PGE1;9-oxo-11α,15R-dihydroxy-16,16-dimethyl-prost-13E-en-1-oic acid;16,16-DIMETHYL PROSTAGLANDIN E1;Prost-13-en-1-oic acid, 11,15-dihydroxy-16,16-dimethyl-9-oxo-, (11α,13E,15R)- | | CAS: | 41692-15-3 | | MF: | C22H38O5 | | MW: | 382.53 | | EINECS: | | | Product Categories: | | | Mol File: | 41692-15-3.mol |  |
| | 16,16-DIMETHYL PROSTAGLANDIN E1 Chemical Properties |
| storage temp. | Store at -20°C | | solubility | DMF: >100 mg/ml; DMSO: >50 mg/ml; Ethanol: >50 mg/ml; PBS pH 7.2: >1.6 mg/ml |
| | 16,16-DIMETHYL PROSTAGLANDIN E1 Usage And Synthesis |
| Description | 16,16-dimethyl PGE1 is a metabolically stable synthetic analog of PGE1. It induces human vascular smooth muscle contractions in vitro. It is 2, 3, and 6 times more potent than PGF2α in contracting tracheal, bronchial, and bronchiolar smooth muscle, respectively.1 | | Uses | 16,16-Dimethylprostaglandin E1 (16,16-dimethyl-PGE1) is a PGE1 (HY-B0131) analog, induces bronchoconstrict and vascular smooth muscle contractions and suppresses the indomethacin induced cellular elongation[1][2][3]. | | Definition | ChEBI: 16,16-dimethyl-PGE1 is a prostanoid. | | in vivo | 16,16-Dimethylprostaglandin E1 (1 μg/kg?min for 30 min) accelerates blood pressure and heart rate recovery rate, increases catecholamine turnover, enhances levels of epinephrine and norepinephrine in plasma following acute hemorrhage in Sprague Dawley rats[1].
| Animal Model: | Sprague-Dawley rats[1] | | Dosage: | 1 μg/kg?min | | Administration: | 0-30 min | | Result: | Improved blood pressure and heart rate, improved levels of epinephrine and norepinephrine im plasma. |
| | References | 1. Karim, S.M.M., Adaikan, P.G., and Kottegoda, S.R. Prostaglandins and human respiratory tract smooth muscle: Structure activity relationship Adv. Prostaglandin Thromboxane Res. 7,969-980(1980). |
| | 16,16-DIMETHYL PROSTAGLANDIN E1 Preparation Products And Raw materials |
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