3-[[[(2S,4S)-4-Mercapto-1-(4-nitrobenzyloxy)carbonyl-2-pyrrolidinyl]carbonyl]amino]benzoic acid

3-[[[(2S,4S)-4-Mercapto-1-(4-nitrobenzyloxy)carbonyl-2-pyrrolidinyl]carbonyl]amino]benzoic acid Suppliers list

Company Name:	Hebei Yanxi Chemical Co., Ltd.
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Products Intro:	Product Name:Side Train of Ertapenem CAS:202467-69-4 Purity:0.99 Package:1kg;50USD\|100kg;25USD\|1000kg;8USD Remarks:Factory direct sales

Company Name:	Hebei Chuanghai Biotechnology Co., Ltd
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Products Intro:	Product Name:3-[[[(2S,4S)-4-Mercapto-1-(4-nitrobenzyloxy)carbonyl-2-pyrrolidinyl]carbonyl]amino]benzoic acid CAS:202467-69-4 Purity:99% Package:1KG;5USD\|1000KG;0.1USD

Company Name:	airuikechemical co., ltd.
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Products Intro:	Product Name:3-[[[(2s,4s)-4-mercapto-1-(4-nitrobenzyloxy)carbonyl-2-pyrrolidinyl]carbonyl]amino]benzoic acid CAS:202467-69-4 Purity:99.99% Package:1g;0.00;USD\|5g;0.00;USD\|25g;0.00;USD

Company Name:	Henan Tianfu Chemical Co.,Ltd.
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Products Intro:	Product Name:TIANFUCHEM--202467-69-4--High purity 3-[[[(2S,4S)-4-Mercapto-1-(4-nitrobenzyloxy)carbonyl-2-pyrrolidinyl]carbonyl]amino]benzoic acid factory price CAS:202467-69-4 Purity:99% Package:25KG;5KG;1KG

3-[[[(2S,4S)-4-Mercapto-1-(4-nitrobenzyloxy)carbonyl-2-pyrrolidinyl]carbonyl]amino]benzoic acid manufacturers

3-[[[(2S,4S)-4-Mercapto-1-(4-nitrobenzyloxy)carbonyl-2-pyrrolidinyl]carbonyl]amino]benzoic acid Basic information

Product Name:	3-[[[(2S,4S)-4-Mercapto-1-(4-nitrobenzyloxy)carbonyl-2-pyrrolidinyl]carbonyl]amino]benzoic acid
Synonyms:	3-([[(2S,4S)-4-Mercapto-1-((4-nitrobenzyloxy)carbonyl)pyrrolidin-2-yl]carbonyl]aMino)benzoic acid;The Sidechain of Ertapenem;2-[(3-carboxyanilino)-oxomethyl]-4-mercapto-4-nitro-2-(phenylmethyl)-1-pyrrolidinecarboxylate;Ertaipenem side chain;Ertapenem side chain, Side chain for Ertapenem;Ertapenem side chains;[(2S,4S)-4-Mercapto-1-(4-nitrobenzyloxy)carbonyl-2-pyrrolidinyl]carbonyl]amino]benzoic acid;Side Train of Ertapenem
CAS:	202467-69-4
MF:	C20H19N3O7S
MW:	445.45
EINECS:	606-474-0
Product Categories:
Mol File:	202467-69-4.mol

3-[[[(2S,4S)-4-Mercapto-1-(4-nitrobenzyloxy)carbonyl-2-pyrrolidinyl]carbonyl]amino]benzoic acid Chemical Properties

Boiling point	749.6±60.0 °C(Predicted)
density	1.50±0.1 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
solubility	DMSO, Methanol (Sparingly)
pka	4.06±0.10(Predicted)
form	Solid
color	Off-White
InChIKey	RTQKWWOSWDCUMA-IRXDYDNUSA-N
SMILES	N1(C(OCC2=CC=C([N+]([O-])=O)C=C2)=O)C[C@@H](S)C[C@H]1C(NC1=CC=CC(C(O)=O)=C1)=O
CAS DataBase Reference	202467-69-4(CAS DataBase Reference)

Safety Information

MSDS Information

3-[[[(2S,4S)-4-Mercapto-1-(4-nitrobenzyloxy)carbonyl-2-pyrrolidinyl]carbonyl]amino]benzoic acid Usage And Synthesis

Uses	3-[[[(2S,4S)-1-(4-Nitrobenzyloxycarbonyl)-4-mercaptopyrrolidin-2-yl]carbonyl]amino]benzoic Acid is an intermediate in the preparation of Ertapenem (E635000) and intermediates.
Synthesis	99-05-8 151072-00-3 202467-69-4 At 60 °C, m-aminobenzoic acid (9.45 g, 68.9 mmol) was dissolved in 200 g of methanol and 1 g of tributylphosphine and 400 ml of a methanolic solution of 4M HCl were added. Subsequently, 220 g of methanol solution of 4-nitrobenzyl (1S,4S)-3-oxo-2-thia-5-azabicyclo[2.2.1]heptane-5-carboxylate (19.8 g, 64.28 mmol) was slowly added. The reaction was stirred at the same temperature for 3 hours. After completion of the reaction, the slurry was cooled and filtered to obtain white crystals. The white crystals were washed with methanol and then dried under vacuum to afford 3-((2S,4S)-4-mercapto-1-(((4-nitrobenzyloxy)oxy)carbonyl)pyrrolidine-2-carboxamido)benzoic acid (127.8 g) in 97% molar yield and 99.2% HPLC purity.
References	[1] Patent: CN105566193, 2016, A. Location in patent: Paragraph 0014; 0015 [2] Patent: CN104130262, 2017, B. Location in patent: Paragraph 0132; 0133; 0134

3-[[[(2S,4S)-4-Mercapto-1-(4-nitrobenzyloxy)carbonyl-2-pyrrolidinyl]carbonyl]amino]benzoic acid Preparation Products And Raw materials

Raw materials

Tag:3-[[[(2S,4S)-4-Mercapto-1-(4-nitrobenzyloxy)carbonyl-2-pyrrolidinyl]carbonyl]amino]benzoic acid(202467-69-4) Related Product Information

Side chain for imipenem (Z)-2-(Methoxycarbonylmethoxyimino)-2-(2-aminothiazol-4-yl)acetic acid CARBONYL SULFIDE Side chain for meropenem 6-Aminocaproic acid Ertapenem PYRAZOPHOS BIAPENEM SIDE CHAIN Ertapenem impurity 3 (4R,5S,6S)-3-[[(3S,5S)-1-[3-[[[(2S,4S)-4-[[(4R,5S,6S)-2-Carboxy-6-[(1R)-1-hydroxyethyl]-4-Methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-en-3-yl]thio]-2-pyrrolidinyl]carbonyl]aMino]benzoyl]-5-[[(3-carboxyphenyl)aMino]carbonyl]-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-Methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic Acid Glycine Ertapenem sodium 3-[(2S,4S)-4-Mercaptopyrrolidine-2-carboxamido]benzoic acid hydrochloride ErtapeneM IMpurity DIPP ErtapeneM Side Chain EnantioMer 1 Ertapenem-d4 Disodium Malathion 3-[[[(2S,4S)-4-Mercapto-1-(4-nitrobenzyloxy)carbonyl-2-pyrrolidinyl]carbonyl]amino]benzoic acid