LCL-PEG3-N3

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LCL-PEG3-N3 Suppliers list
Company Name: Henan Mengtai Pharmaceutical Technology Co., Ltd  
Tel: 17634413542
Email: 1959525201@qq.com
Company Name: TargetMol  
Tel: 400-821-0310 15002144251
Email: xuexiang.shao@tsbiochem.com
LCL-PEG3-N3 Basic information
Product Name:LCL-PEG3-N3
Synonyms:
CAS:3033849-90-7
MF:C32H45N7O6S
MW:655.81
EINECS:
Product Categories:
Mol File:3033849-90-7.mol
LCL-PEG3-N3 Structure
LCL-PEG3-N3 Chemical Properties
Safety Information
MSDS Information
LCL-PEG3-N3 Usage And Synthesis
UsesLCL-PEG3-N3 is a decoy oligonucleotide ligand for E3 ligase which can be used for developing chimeric molecules LCL-ER(dec), degrading the estrogen receptor[1]. LCL-PEG3-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50IAP
References[1] Miyako Naganuma, et al. Development of Chimeric Molecules That Degrade the Estrogen Receptor Using Decoy Oligonucleotide Ligands. ACS Med Chem Lett. 2022;13(1):134-139.
LCL-PEG3-N3 Preparation Products And Raw materials
Tag:LCL-PEG3-N3(3033849-90-7) Related Product Information
(2S,4R)-1-((S)-2-(tert-Butyl)-4-oxo-6,9,12-trioxa-3-azapentadec-14-yn-1-oyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide Thalidomide-NH-PEG2-C2-NH2 hydrochloride Pomalidomide-PEG3-N3 CAS:2722697-82-5 -PEG4-amine E3 ligase Ligand-Linker Conjugates 3