- Nafamostat
-
- $15.00
-
2021-07-13
- CAS:81525-10-2
- Min. Order: 1KG
- Purity: 99%+ HPLC
- Nafamostat
-
- $15.00
-
2021-07-10
- CAS:81525-10-2
- Min. Order: 1KG
- Purity: 99%+ HPLC
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| | Nafamostat Basic information |
| Product Name: | Nafamostat | | Synonyms: | 6-AMIDINO-2-NAPHTHYL-4-GUANIDINOENZOATE, MESYLATE;FUTHAN;NafamostatMesilateBase;6-Amidino-2-naphthyl 4-guanidinobenzoate;Nafamostat Dimethanesulfonate;Nafamstat;4-(Amidinoamino)benzoic acid 6-amidino-2-naphtyl ester;4-Guanidinobenzoic acid 6-amidino-2-naphtyl ester | | CAS: | 81525-10-2 | | MF: | C19H17N5O2 | | MW: | 347.37 | | EINECS: | 1806241-263-5 | | Product Categories: | | | Mol File: | 81525-10-2.mol |  |
| | Nafamostat Chemical Properties |
| Boiling point | 586.0±60.0 °C(Predicted) | | density | 1.39±0.1 g/cm3(Predicted) | | storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C | | solubility | Soluble in DMSO | | form | Powder | | pka | 11.30±0.30(Predicted) |
| | Nafamostat Usage And Synthesis |
| Chemical Properties | Odorless, bitter taste. Easily soluble in water, insoluble in methanol, ethanol or dimethylformamide, almost insoluble in ether, chloroform or acetone. Density: 1.39g/cm3; Boiling Point: 637.2°C; Flash Point: 339.1°C; Vapor Pressure: 3.9E-16mmHg. | | Uses | Nafamostat is a non-peptide synthetic protease inhibitor with broad-spectrum and potent enzyme inhibition. For the treatment of acute pancreatitis. It can improve acute symptoms of acute pancreatitis, acute exacerbation of chronic pancreatitis, and post-traumatic pancreatitis. | | Definition | ChEBI: Nafamostat is a member of benzoic acids and a member of guanidines. | | Preparation | 6-Bromo-2-naphthol reacts with copper cyanide in dimethylformamide to generate 6-cyano-2-naphthol, which is methanolylated and then aminolyzed to generate 6-amidino-2-naphthol , and finally esterification with p-guanidinobenzoic acid to generate nafamostat. |
| | Nafamostat Preparation Products And Raw materials |
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