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goldenchemical Gold |
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18651817751 |
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| | Cyclopropanesulfonamide Basic information |
| Product Name: | Cyclopropanesulfonamide | | Synonyms: | 4-METHANESULFONYLCHLOROBENZENE;4-CHLOROPHENYL METHYL SULPHONE;1-CHLORO-4-(METHANESULFONYL)-BENZENE;Cyclopropanesulphonamide 98%;CYCLOPROPANE SULFONAMIDE;CYCLOPROPANESULFONYL AMIDE;TIMTEC-BB SBB006326;P-CHLOROPHENYL METHYL SULFONE | | CAS: | 154350-29-5 | | MF: | C3H7NO2S | | MW: | 121.16 | | EINECS: | 604-946-0 | | Product Categories: | sulfonyl compound;SULFONAMIDE | | Mol File: | 154350-29-5.mol |  |
| | Cyclopropanesulfonamide Chemical Properties |
| Melting point | 95-98 °C(lit.) | | Boiling point | 263.1±23.0 °C(Predicted) | | density | 1.44±0.1 g/cm3(Predicted) | | storage temp. | Sealed in dry,Room Temperature | | Water Solubility | Soluble in water. | | form | powder to crystal | | pka | 10.69±0.20(Predicted) | | color | White to Almost white | | InChI | InChI=1S/C3H7NO2S/c4-7(5,6)3-1-2-3/h3H,1-2H2,(H2,4,5,6) | | InChIKey | WMSPXQIQBQAWLL-UHFFFAOYSA-N | | SMILES | C1(S(N)(=O)=O)CC1 | | CAS DataBase Reference | 154350-29-5(CAS DataBase Reference) |
| Hazard Codes | Xn | | Risk Statements | 22-38 | | Safety Statements | 26-28-36/37/39 | | WGK Germany | 3 | | RTECS | WR5730000 | | HS Code | 2935909099 |
| | Cyclopropanesulfonamide Usage And Synthesis |
| Chemical Properties | Cyclopropanesulfonamide is a white solid. It is special antidote for the corn herbicide nicosulfuron, which increases the speed of corn herbicide degradation. | | Uses | Cyclopropanesulfonamide is used as fine chemicals to the pharmaceutical, agrochemical, aroma, polymer and electronic industries. | | Synthesis | Cyclopropanesulfonamide was synthesized as follows: Standard method D (0054) was used, with cyclopropanesulfonyl chloride as the starting material. The procedure was as follows: cyclopropanesulfonyl chloride (0.400 mL, 3.95 mmol) was dissolved in methanol (3.0 mL) and ammonium hydroxide solution (15 mL) at 0 °C or room temperature and the reaction mixture was stirred. After the reaction lasted for 16 hours, methanol was removed by distillation under reduced pressure. Subsequently, the reaction mixture was extracted with ethyl acetate. After combining the organic layers, the reaction was dried using anhydrous magnesium sulfate (MgSO4), filtered and concentrated to give the target product cyclopropanesulfonamide directly without further purification. The final cyclopropanesulfonamide was obtained as a white solid (0.249 g, 52% yield). The structure of the product was confirmed by 1H NMR (DMSO-d6, 300 MHz), and the characteristic peaks were: δ 6.78 (br s, 2H), 2.50-2.46 (m, 1H), 0.89-0.86 (m, 4H). | | References | [1] Patent: US2006/183694, 2006, A1. Location in patent: Page/Page column 25
[2] Patent: US2007/10455, 2007, A1. Location in patent: Page/Page column 26
[3] Patent: US2008/14173, 2008, A1. Location in patent: Page/Page column 26
[4] Patent: US2008/107625, 2008, A1. Location in patent: Page/Page column 24
[5] Patent: WO2003/99274, 2003, A1. Location in patent: Page 65 |
| | Cyclopropanesulfonamide Preparation Products And Raw materials |
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