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| | 6-BROMO-4-METHYLQUINOLIN-2(1H)-ONE Basic information |
| Product Name: | 6-BROMO-4-METHYLQUINOLIN-2(1H)-ONE | | Synonyms: | 6-BROMO-4-METHYLQUINOLIN-2(1H)-ONE;6-bromo-4-methyl-2(1H)-quinolinone(SALTDATA: FREE);6-broMo-4-Methyl-1,2-dihydroquinolin-2-one;6-Bromo-4-methyl-2(1H)-quinolinone;2(1H)-Quinolinone, 6-bromo-4-methyl-;6-Bromo-4-methyl-2-quinolinol | | CAS: | 89446-19-5 | | MF: | C10H8BrNO | | MW: | 238.08 | | EINECS: | | | Product Categories: | | | Mol File: | 89446-19-5.mol |  |
| | 6-BROMO-4-METHYLQUINOLIN-2(1H)-ONE Chemical Properties |
| Melting point | 290-292 °C | | Boiling point | 392.6±42.0 °C(Predicted) | | density | 1.523±0.06 g/cm3(Predicted) | | storage temp. | Sealed in dry,Room Temperature | | pka | 10.79±0.70(Predicted) | | Appearance | White to light brown Solid |
| | 6-BROMO-4-METHYLQUINOLIN-2(1H)-ONE Usage And Synthesis |
| Synthesis | (b) N-(4-bromophenyl)-3-oxobutanamide (0.73 g, 2.85 mmol) was dissolved in concentrated hydrochloric acid. The reaction was heated to 120 °C in an oil bath and sodium sulfate (7 mL) was added and kept at this temperature for 1 hour. Upon completion of the reaction, the mixture was cooled to room temperature and subsequently poured into a beaker containing ice. The precipitate precipitated was collected by filtration to afford 6-bromo-4-methyl-2(1H)-quinolinone as a tan solid (0.4 g, 60% yield). | | References | [1] Patent: WO2010/132615, 2010, A1. Location in patent: Page/Page column 138
[2] Synthesis, 2011, # 6, p. 934 - 942
[3] Patent: US2005/234101, 2005, A1. Location in patent: Page/Page column 14
[4] Patent: WO2005/103002, 2005, A2. Location in patent: Page/Page column 44
[5] Patent: US2005/267115, 2005, A1. Location in patent: Page/Page column 21 |
| | 6-BROMO-4-METHYLQUINOLIN-2(1H)-ONE Preparation Products And Raw materials |
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