E3 ligase Ligand-Linker Conjugates 14

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E3 ligase Ligand-Linker Conjugates 14 Basic information
Product Name:E3 ligase Ligand-Linker Conjugates 14
Synonyms:E3 ligase Ligand-Linker Conjugates 14;E3 ligase Ligand-Linker Conjugates 14 (TFA);Cereblon Ligand-Linker Conjugates 3 (TFA);Pomalidomide Related Compound 5 Triflate;E3 Ligase Ligand-Linker Conjugates,Cereblon Ligand-Linker Conjugates 3,Thalidomide O amido PEG3 C2 NH2 TFA,Thalidomide-O-amido-PEG-3-C2-NH2 TFA,E3 ligase Ligand-Linker Conjugates 14,inhibit,Inhibitor,ThalidomideOamidoPEG3C2NH2 TFA;Acetamide,?N-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethyl]-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-, 2,2,2-trifluoroacetate (1:1)
CAS:1957236-21-3
MF:C25H31F3N4O11
MW:620.54
EINECS:
Product Categories:
Mol File:1957236-21-3.mol
E3 ligase Ligand-Linker Conjugates 14 Structure
E3 ligase Ligand-Linker Conjugates 14 Chemical Properties
storage temp. 2-8°C, sealed storage, away from moisture
form Solid
color White to off-white
Safety Information
MSDS Information
E3 ligase Ligand-Linker Conjugates 14 Usage And Synthesis
UsesThalidomide-O-amido-PEG3-C2-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology.
IC 50Cereblon
References[1] BRADNER, James, et al. METHODS TO INDUCE TARGETED PROTEIN DEGRADATION THROUGH BIFUNCTIONAL MOLECULES. WO2017024317A2.
E3 ligase Ligand-Linker Conjugates 14 Preparation Products And Raw materials
Tag:E3 ligase Ligand-Linker Conjugates 14(1957236-21-3) Related Product Information
4-((2-(2-(2-(2-(4-aminophenoxy)ethoxy)ethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione E3 ligase Ligand-Linker Conjugates 17 E3 ligase Ligand-Linker Conjugates 5 Free Base N-(4-aminobutyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide TFA salt E3 Ligase Ligand-Linker Conjugates 25 Trifluoroacetate Thalidomide-O-amido-C3-NH2 (TFA) E3 Ligase Ligand-Linker Conjugates 19 E3 Ligase Ligand-Linker Conjugates 1