E3 ligase Ligand-Linker Conjugates 17

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Products Intro: Product Name:Cereblon Ligand -Linker Conjugates 2 TFA
CAS:1950635-16-1
Purity:0.99 Package:5MG;10MG;50MG;100MG,1G,5G
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Products Intro: Product Name:Thalidomide-O-amido-C8-NH2 (TFA)
CAS:1950635-16-1
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Products Intro: Product Name:E3 Ligase Ligand-Linker Conjugates 20 TFA
CAS:1950635-16-1
Purity:98% Package:5mg Remarks:V32005
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Products Intro: Product Name:N-(8-aminooctyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide trifluoroacetate
CAS:1950635-16-1
Purity:95%+ Package:1g;5g;10g;25g;50g;100g; Remarks:accept Custom Synthesis Services, support large packing
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Products Intro: Product Name:E3 ligase Ligand-Linker Conjugates 17
CAS:1950635-16-1
Purity:>98.0% Package:10mg;100mg
E3 ligase Ligand-Linker Conjugates 17 Basic information
Product Name:E3 ligase Ligand-Linker Conjugates 17
Synonyms:E3 ligase Ligand-Linker Conjugates 17;E3 Ligase Ligand-Linker Conjugates 20 (TFA);Cereblon Ligand -Linker Conjugates 2 TFA;Pomalidomide Related Compound 6 Triflate;N-(8-Aminooctyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide 2,2,2-trifluoroacetate;N-(8-aminooctyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide trifluoroacetate;Thalidomide-O-amido-C8-NH2 trifluoroacetate
CAS:1950635-16-1
MF:C25H31F3N4O8
MW:572.54
EINECS:
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Mol File:1950635-16-1.mol
E3 ligase Ligand-Linker Conjugates 17 Structure
E3 ligase Ligand-Linker Conjugates 17 Chemical Properties
storage temp. 2-8°C
form Solid
color White to off-white
Safety Information
MSDS Information
E3 ligase Ligand-Linker Conjugates 17 Usage And Synthesis
UsesThalidomide-O-amido-C8-NH2 TFA (Cereblon Ligand -Linker Conjugates 2 TFA) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.
IC 50Cereblon
References[1] James Bradner, et al. Methods to induce targeted protein degradation through bifunctional molecules. WO 2017024317 A2.
E3 ligase Ligand-Linker Conjugates 17 Preparation Products And Raw materials
Tag:E3 ligase Ligand-Linker Conjugates 17(1950635-16-1) Related Product Information
E3 Ligase Ligand-Linker Conjugates 25 Trifluoroacetate E3 ligase Ligand-Linker Conjugates 5 Free Base Thalidomide-O-amido-C3-NH2 (TFA) E3 Ligase Ligand-Linker Conjugates 19 E3 Ligase Ligand-Linker Conjugates 1 N-(4-aminobutyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide TFA salt E3 ligase Ligand-Linker Conjugates 14 4-((2-(2-(2-(2-(4-aminophenoxy)ethoxy)ethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione

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