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| | D-(+)-Digitoxose Basic information |
| | D-(+)-Digitoxose Chemical Properties |
| Melting point | 98-100 °C | | alpha | D17 +46.3° (in water); D20 +39.1° (in methanol); D18 +27.9° +43.3° (after 24 hrs in pyridine) | | Boiling point | 188.74°C (rough estimate) | | density | 1.0610 (rough estimate) | | refractive index | 1.4320 (estimate) | | storage temp. | Refrigerator | | solubility | DMSO (Slightly), Methanol (Slightly), Water (Slightly) | | form | Solid | | pKa | 13.72±0.20(Predicted) | | color | White to Pale Yellow | | Optical Rotation | +46.4 | | CAS DataBase Reference | 527-52-6(CAS DataBase Reference) |
| WGK Germany | 3 | | F | 3-10 | | HS Code | 29329990 |
| | D-(+)-Digitoxose Usage And Synthesis |
| Uses | D-Digitoxose is a derivative of D-ribo-Hexonic acid that is metabolized in the liver. It inhibits glucose-stimulated insulin release. | | Definition | ChEBI: Digitoxose is a dideoxyhexose. | | Purification Methods | Crystallise D(+)-digitoxose from MeOH/Et2O, Et2O, EtOAc, EtOAc/Et2O/pet ether or Me2CO/Et2O and dry it over P2O5/vacuum. It has [] D +45.2o (6minutes) mutarotating to +50.2o (16hours constant) (c 1.65, H2O). [Gut & Prins Helv Chim Acta 20 1229 1947, Bollinger & Ulrich Helv Chim Acta 35 93 1952, NMR of derivs: Tsukamoto et al. J Chem Soc, Perkin Trans 1 2621 1988, Beilstein 1 IV 4191.] |
| | D-(+)-Digitoxose Preparation Products And Raw materials |
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