|
|
| | L-(-)-Vesamicol hydrochloride Basic information |
| Product Name: | L-(-)-Vesamicol hydrochloride | | Synonyms: | 1r-trans-cyclohexano;L(-)-VESAMICOL HCL;L-(-)-2-(4-Phenylpiperidino)cyclohexanol hydrochloride;(1R,2R)-2-(4-phenylpiperidin-1-yl)cyclohexan-1-ol;Cyclohexanol, 2-(4-phenyl-1-piperidinyl)-, (1R,2R)-;(-)-Vesamicol (AH5183);L-(-)-Vesamicol hydrochloride | | CAS: | 112709-59-8 | | MF: | C17H25NO | | MW: | 259.39 | | EINECS: | | | Product Categories: | | | Mol File: | 112709-59-8.mol |  |
| | L-(-)-Vesamicol hydrochloride Chemical Properties |
| Melting point | 238.5-240.0 °C | | Boiling point | 393.5±42.0 °C(Predicted) | | density | 1.086±0.06 g/cm3(Predicted) | | pka | 15.16±0.40(Predicted) | | form | solid | | color | white |
| Safety Statements | 22-24/25 | | WGK Germany | 3 | | RTECS | GW0765050 |
| | L-(-)-Vesamicol hydrochloride Usage And Synthesis |
| Uses | (-)-Vesamicol (AH5183) is an inhibitor of acetylcholine transport into synaptic vesicles, with the IC50 of 75 nM[1]. (-)-Vesamicol can be used for release and recycling of synaptic vesicles study[1]. | | Definition | ChEBI: (1R,2R)-2-(4-phenyl-1-piperidinyl)-1-cyclohexanol is a member of piperidines. | | References | [1] Searl T, et al. Acetylcholine recycling and release at rat motor nerve terminals studied using (-)-vesamicol and troxpyrrolium. J Physiol. 1991;444:99-116. DOI:10.1113/jphysiol.1991.sp018868 |
| | L-(-)-Vesamicol hydrochloride Preparation Products And Raw materials |
|