(+/-)-VESAMICOL HYDROCHLORIDE manufacturers
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| | (+/-)-VESAMICOL HYDROCHLORIDE Basic information |
| Product Name: | (+/-)-VESAMICOL HYDROCHLORIDE | | Synonyms: | AH-5183;AH-5183 HYDROCHLORIDE;(+/-)-2-(4-PHENYLPIPERIDINO)CYCLOHEXANOL HYDROCHLORIDE;(+/-)-VESAMICOL HCL;(+/-)-VESAMICOL HYDROCHLORIDE;(+/-)-VESAMICOL HYDROCHLORIDE (AH-5183) >98%;(±)-2-(4-Phenylpiperidino)cyclohexanol hydrochloride, AH-5183 hydrochloride;Ah-5183((+/-)-2-(4-phenylpiperidino) cyclohexanol | | CAS: | 120447-62-3 | | MF: | C17H25NO.ClH | | MW: | 295.85 | | EINECS: | | | Product Categories: | | | Mol File: | 120447-62-3.mol |  |
| | (+/-)-VESAMICOL HYDROCHLORIDE Chemical Properties |
| storage temp. | Store at RT | | solubility | aqueous buffers below pH 8: 1 mM | | form | solid | | color | white |
| | (+/-)-VESAMICOL HYDROCHLORIDE Usage And Synthesis |
| Uses | (+/-)-VesamicolmiddotHCl (AH-5183) is a blocker of acetylcholine transfer into nerve terminal vesicles. | | in vivo | (±)-Vesamicol (3 mg/kg; intraperitoneal injection; once; male Wistar rats) treatment increases the levels of cytosolic acetylcholine (ACh) in all regions of the brain, while those of vesicular ACh decreased in all regions except for the striatum[2]. | Animal Model: | Male Wistar rats (120-300 g)[2] | | Dosage: | 3 mg/kg | | Administration: | Intraperitoneal injection; once | | Result: | The levels of cytosolic acetylcholine (ACh) increased in all regions of the brain, while those of vesicular ACh decreased in all regions except for the striatum.
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| | IC 50 | Sigma 1 Receptor; Sigma 2 Receptor |
| | (+/-)-VESAMICOL HYDROCHLORIDE Preparation Products And Raw materials |
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