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Rifalazil

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Rifalazil manufacturers

  • Rifalazil
  • Rifalazil pictures
  • $99.00
  • 2026-07-16
  • CAS:129791-92-0
  • Purity:
  • Supply Ability: 10g
  • Rifalazil
  • Rifalazil pictures
  • $107.00
  • 2025-07-09
  • CAS:129791-92-0
  • Purity:
  • Supply Ability: 10g
Rifalazil Basic information
Product Name:Rifalazil
Synonyms:RIFALAZIL;KRM 1648;3'-Hydroxy-5'-(4-isobutylpiperazinyl)benzoxazinorifamycin;1-Deoxy-1'-dehydro-1-oxo-3'-hydroxy-5'-[4-(2-methylpropyl)piperazino]rifamycin VIII;5,12-Dihydroxy-2,4-dimethyl-10-[4-(2-methyl-propyl)-l-piperazinyl]-2,7-[oxy(5-acetoxy-7,9-dihydroxy-3-methoxy-4,6,8,10,14-pentamethyl-15-oxo-l,ll,13-pentadecatriene-l,15-diyl)imino]-6H-benzofuro[4,5-a]phenoxazine-l(2H),6-dione;Rifalazil USP/EP/BP;Rifamycin Impurity 43
CAS:129791-92-0
MF:C51H64N4O13
MW:941.07
EINECS:
Product Categories:
Mol File:129791-92-0.mol
Rifalazil Structure
Rifalazil Chemical Properties
Melting point 195-200° (dec)
Boiling point 1065.6±65.0 °C(Predicted)
density 1.36±0.1 g/cm3(Predicted)
storage temp. 4°C, away from moisture
solubility DMSO: 8.33 mg/mL (8.85 mM)
pka4.28±0.70(Predicted)
form Solid
color Blue to dark blue
Safety Information
MSDS Information
Rifalazil Usage And Synthesis
UsesAntibacterial (antimycobacterial).
UsesRifalazil has been used as a part of multi drug regimen in the treatment of tuberculosis.
DefinitionChEBI: Rifalazil is a phenoxazine.
in vivo

Rifalazil (oral gavage; 20, 25, and 150 mg/kg; 6-8 weeks) combines with isoniazid (INH) for 6 weeks or greater significantly reduced the number of mice per group in which M. tuberculosis is detected in both spleens and lungs compared to the reductions for the early and late controls. And the addition of Pyrazinamide (PZA) does not significantly improve RLZ-INH therapy at any time point[2].

Animal Model:Female CD-1 mice infected with 5.2 × 107viable mycobacteria[2]
Dosage:20, 25, and 150 mg/kg; 6-8 weeks
Administration:Oral gavage
Result:Combined with isoniazid (INH) showed its potential for short-course treatment ofMycobacterium tuberculosisinfection.
Rifalazil Preparation Products And Raw materials
Tag:Rifalazil(129791-92-0) Related Product Information
RIFAMYCIN SV Dimethyl ether Propyl butyrate CHLOROPHOSPHONAZO III Solvent Red 43 Propyl gallate Rifamycin Sodium Rifapentine ETHANE Dimethyl fumarate Dimethyl carbonate Isopropyl alcohol Dimethyl sulfoxide N,N-Dimethylformamide PHENYLGLYOXAL MONOHYDRATE Nile Red 2-Amino-4'-methoxyacetophenone 1-(3-Methoxyphenyl)piperazine