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| | P-TOLUENESULFONYL FLUORIDE Basic information |
| | P-TOLUENESULFONYL FLUORIDE Chemical Properties |
| Melting point | 41-42 °C(lit.) | | Boiling point | 112 °C16 mm Hg(lit.) | | density | 1.2768 (estimate) | | Fp | 222 °F | | storage temp. | Storage temp. 2-8°C | | form | solid | | Appearance | White to off-white Solid | | Water Solubility | Hydrolyzes in water. | | Sensitive | Moisture Sensitive | | BRN | 2208423 | | Exposure limits | ACGIH: TWA 2.5 mg/m3
NIOSH: IDLH 250 mg/m3 | | CAS DataBase Reference | 455-16-3(CAS DataBase Reference) | | EPA Substance Registry System | Benzenesulfonyl fluoride, 4-methyl- (455-16-3) |
| Hazard Codes | C | | Risk Statements | 20/21/22-34 | | Safety Statements | 22-26-27-36/37/39-45 | | RIDADR | UN 3261 8/PG 2 | | WGK Germany | 3 | | RTECS | XT8050000 | | Hazard Note | Corrosive | | TSCA | TSCA listed | | HazardClass | 8 | | PackingGroup | II | | HS Code | 29049095 | | Toxicity | rat,LD50,intraperitoneal,200mg/kg (200mg/kg),Nature. Vol. 173, Pg. 33, 1954. |
| | P-TOLUENESULFONYL FLUORIDE Usage And Synthesis |
| Chemical Properties | White to beige fused mass | | Uses | Protease inhibitor. | | Uses | p-Toluenesulfonyl fluoride is used for sulfonylation of organometallic reagents as a simple, one-step synthesis of sulfones. It is useful in the treatment of Alzheimers disease. It is used to study the DNS polymerase from spinach leaf extracts. It was used in isolation and separation of Pseudomonas aeruginosa membranes by density sucrose gradient centrifugation. | | General Description | p-Toluenesulfonyl fluoride is a peroxygen bleach activator and is also useful in the treatment of Alzheimer′s disease. | | reaction suitability | reaction type: click chemistry |
| | P-TOLUENESULFONYL FLUORIDE Preparation Products And Raw materials |
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