3-TRIMETHYLSILYL-2-PROPYN-1-OL

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Products Intro:	Product Name:3-TRIMETHYLSILYL-2-PROPYN-1-OL CAS:5272-36-6 Purity:99% Package:1KG,5kg,10kg Remarks:Low M.W.Organic Silanes Professor

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3-TRIMETHYLSILYL-2-PROPYN-1-OL manufacturers

3-TRIMETHYLSILYL-2-PROPYN-1-OL Basic information

Product Name:	3-TRIMETHYLSILYL-2-PROPYN-1-OL
Synonyms:	3-TRIMETHYLSILYLPROPARGYL ALCOHOL, 98%3-TRIMETHYLSILYLPROPARGYL ALCOHOL, 98%3-TRIMETHYLSILYLPROPARGYL ALCOHOL, 98%;3-Trimethylsilyl-2-propyn-1-ol,99%;3-(triMethylsilyl)prop-2-yn-1-ol;3-Trimethylsilylpropargyl;3-(Trimethylsilyl)propargyl alcohol 99%;TIMTEC-BB SBB009061;TRIMETHYLSILYLPROPARGYL ALCOHOL;1-TRIMETHYLSILYLPROPARGYL ALCOHOL
CAS:	5272-36-6
MF:	C6H12OSi
MW:	128.24
EINECS:	226-094-5
Product Categories:	Acetylenic Alcohols & Their Derivatives;Ethynylsilanes;Si (Classes of Silicon Compounds);Si-(C)4 Compounds;Silicon Compounds (for Synthesis);Synthetic Organic Chemistry;Acetylenes
Mol File:	5272-36-6.mol

3-TRIMETHYLSILYL-2-PROPYN-1-OL Chemical Properties

Melting point	63.5-65.0 °C
Boiling point	76 °C11 mm Hg(lit.)
density	0.865 g/mL at 25 °C(lit.)
refractive index	n20/D 1.451(lit.)
Fp	152 °F
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	Benzene (Sparingly)
pka	13.71±0.10(Predicted)
form	Liquid
color	Clear yellow
Specific Gravity	0.865
Water Solubility	Not miscible with water.
Sensitive	Moisture Sensitive
Hydrolytic Sensitivity	4: no reaction with water under neutral conditions
BRN	1902505
InChIKey	ZVGCJDPEKKEYES-UHFFFAOYSA-N
CAS DataBase Reference	5272-36-6(CAS DataBase Reference)
NIST Chemistry Reference	3-Trimethylsilylpropargyl alcohol(5272-36-6)
EPA Substance Registry System	2-Propyn-1-ol, 3-(trimethylsilyl)- (5272-36-6)

Safety Information

MSDS Information

3-TRIMETHYLSILYL-2-PROPYN-1-OL Usage And Synthesis

Chemical Properties	clear yellow liquid
Uses	Trimethylsilylpropargyl alcohol is used as a reagent to synthesize Isbogrel, a Thromboxane A 2 (TXA 2) synthase inhibitor and also a TXA 2 receptor antagonist that has potential to treat asthma.

3-TRIMETHYLSILYL-2-PROPYN-1-OL Preparation Products And Raw materials

Raw materials	Bis[tris(trimethylsilyl)silyl]zinc-->Tetrahydro-2-[[3-(trimethylsilyl)-2-propyn-1-yl]oxy]-2H-Pyran-->PROPARGYLOXYTRIMETHYLSILANE-->TETRAHYDRO-2-(2-PROPYNYLOXY)-2H-PYRAN-->1-trimethylsilyloxy-3-trimethylsilylprop-2-yne-->PHENYLETHYNYLMAGNESIUM BROMIDE-->1-PHENYL-2-(TRIMETHYLSILYL)ACETYLENE-->Bromoethane-->Dichlorodimethylsilane-->Propargyl alcohol
Preparation Products	3-BROMO-1-(TRIMETHYLSILYL)-1-PROPYNE-->1-Trimethylsilyl-1-butyne-->3-TRIMETHYLSILYLPROPYNAL-->3-Iodo-1-trimethylsilylpropyne

Tag:3-TRIMETHYLSILYL-2-PROPYN-1-OL(5272-36-6) Related Product Information

Trifluoroacetamide SULFUR TRIOXIDE TRIMETHYLAMINE COMPLEX Boron trifluoride tetrahydrofuran complex METHYL 3-(TRIMETHYLSILYL)PROPIOLATE 3-TRIMETHYLSILYL-2-PROPYN-1-OL 4-TRIMETHYLSILYL-3-BUTYN-2-OL 2-METHYL-4-TRIMETHYLSILYL-3-BUTYN-2-OL 3-(TRIMETHYLSILYL)PROPIOLIC ACID 3-TERT-BUTYLDIMETHYLSILYL-2-PROPYN-1-OL Propyne Propargyl alcohol 3-METHYL-1-TRIMETHYLSILYL-1-PENTYN-3-OL (+/-) TRIMETHYLSILYL(TRIMETHYLSILYL)PROPYNOATE ETHYL 3-(TRIMETHYLSILYL)PROPIOLATE 5-TRIMETHYLSILYL-1-PENTEN-4-YN-3-OL 3-TRIMETHYLSILYLPROPARGYL ALDEHYDE DIETHYL ACETAL 2-HYDROXY-4-(TRIMETHYLSILYL)-3-BUTYNOIC ACID ETHYL ESTER 1-CYCLOHEXYL-3-(TERT-BUTYLDIMETHYLSILYL)-2-PROPYN-1-OL

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