BocNH-PEG3-CH2CH2COONHS manufacturers
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| | BocNH-PEG3-CH2CH2COONHS Basic information |
| Product Name: | BocNH-PEG3-CH2CH2COONHS | | Synonyms: | BocNH-PEG3-CH2CH2COONHS;2,5-Dioxopyrrolidin-1-yl 2,2-dimethyl-4-oxo-3,8,11,14-tetraoxa-5-azaheptadecan-17-oate;inhibit,Inhibitor,PROTAC Linkers,Boc NH PEG3 NHS ester,BocNHPEG3NHS ester,Boc-NH-PEG-3-NHS ester;BocNH-PEG3-CH2CH2COONHS/2,5-Dioxopyrrolidin-1-yl 2,2-dimethyl-4-oxo-3,8,11,14-tetraoxa-5-azaheptadecan-17-oate;(2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[(2-methylpropan-2-yl)oxycarbonylamino]ethoxy]ethoxy]ethoxy]propanoate;2,5-Dioxo-1-pyrrolidinyl 3-[2-[2-[2-(Boc-amino)ethoxy]ethoxy]ethoxy]propanoate;BocNH-PEG3-CH2CH2COONHS ester;t-Boc-N-amido-PEG3-NHS | | CAS: | 2250216-93-2 | | MF: | C18H30N2O9 | | MW: | 418.44 | | EINECS: | | | Product Categories: | | | Mol File: | 2250216-93-2.mol |  |
| | BocNH-PEG3-CH2CH2COONHS Chemical Properties |
| density | 1.23±0.1 g/cm3(Predicted) | | storage temp. | Storage temp. -20°C | | solubility | Soluble in DMSO, DCM, DMF | | pka | 12.22±0.46(Predicted) | | form | Liquid | | color | Colorless to light yellow |
| | BocNH-PEG3-CH2CH2COONHS Usage And Synthesis |
| Description | t-Boc-N-amido-PEG3-NHS ester is a PEG linker containing an NHS ester and a t-Boc protected amine group. The hydrophilic PEG spacer increases the solubility of compounds in aqueous media. The t-Boc group can be deprotected under mild acidic conditions to form a free amine. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. | | Uses | Boc-NH-PEG3-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | | IC 50 | PEGs | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | BocNH-PEG3-CH2CH2COONHS Preparation Products And Raw materials |
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