- Isoliquiritin
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- $39.00
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2026-07-27
- CAS:5041-81-6
- Purity: 98.65%
- Supply Ability: 10g
- Isoliquiritin
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-
2023-02-24
- CAS:5041-81-6
- Min. Order: 5mg
- Purity: ≥98%(HPLC)
- Supply Ability: 10 g
- isoliquiritin
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- $15.00
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2021-07-13
- CAS:5041-81-6
- Min. Order: 1KG
- Purity: 99%+ HPLC
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| | ISOLIQUIRITIN Basic information |
| | ISOLIQUIRITIN Chemical Properties |
| Melting point | 185-186℃ | | Boiling point | 743.5±60.0 °C(Predicted) | | density | 1.528 | | storage temp. | 4°C, protect from light | | solubility | Soluble in methan | | form | powder | | pka | 7.46±0.35(Predicted) | | color | Ochre | | biological source | plant | | Major Application | metabolomics
vitamins, nutraceuticals, and natural products | | InChI | InChI=1/C21H22O9/c22-10-17-18(26)19(27)20(28)21(30-17)29-13-5-1-11(2-6-13)3-8-15(24)14-7-4-12(23)9-16(14)25/h1-9,17-23,25-28H,10H2/b8-3+/t17-,18-,19+,20-,21-/s3 | | InChIKey | YNWXJFQOCHMPCK-RQOZFYCLNA-N | | SMILES | [C@@H]1([C@H](O)[C@H]([C@H](O)[C@@H](CO)O1)O)OC1=CC=C(/C=C/C(=O)C2C=CC(O)=CC=2O)C=C1 |&1:0,1,3,4,6,r| |
| WGK Germany | WGK 3 | | Storage Class | 11 - Combustible Solids |
| | ISOLIQUIRITIN Usage And Synthesis |
| Chemical Properties | Yellow crystalline powder, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from licorice. | | Uses | It is a natural product derived from plant source th at finds application in compound screening libraries, metabolomics, phytochemical, and pharmaceutical research. | | Definition | ChEBI: A monosaccharide derivative that is trans-chalcone substituted by hydroxy groups at positions 2' and 4' and a beta-D-glucopyranosyloxy group at position 4 respectively. | | Biological Activity | Isoliquiritin triggers apoptotic cell death by increasing the levels of p53 and p21 in A549 non-small cell lung cancer cells while also inhibiting the p53-dependent pathway and revealing interactions with Akt activities. Futher, Isoliquiritin has demonstrated neuroprotective activity against oxidative stress and has the capability to restrain the growth of microbial pathogens. | | in vivo | Isoliquiritin (0.31-3.1 mg/kg, i.p., once a day for 5 days) inhibits granuloma angiogenesis in mice[1].
Isoliquiritin (10-40 mg/kg, oral gavage) shows antidepressant-like effects in FST and TST tests in mice[2].
Isoliquiritin ((10 mg/kg/bw/day, p.o.) shows anti-oxidative and anti-Inflammatory properties, and relieves cationic BSA-Induced membranous glomerulonephritis in experimental rat model[5].
| Animal Model: | Mice in Forced Swimming Test (FST) and the Tail Suspension Test (TST)[2] | | Dosage: | 10, 20 and 40 mg/kg | | Administration: | oral gavage | | Result: | Reduced the immobility time in the FST and TST in mice.
Increased 5-HT and NE level and Reduced the ratio of 5-HIAA/5-HT in the hippocampus, hypothalamus and cortex. |
| | target | HIV |
| | ISOLIQUIRITIN Preparation Products And Raw materials |
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