| Company Name: |
Fuan Bio |
| Tel: |
15002819872 |
| Email: |
2845971812@qq.com |
TRV120055 manufacturers
- TRV120055
-
- $893.00
-
2026-07-15
- CAS:2410957-04-7
- Purity:
- Supply Ability: 10g
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| | TRV120055 Basic information |
| | TRV120055 Chemical Properties |
| density | 1.40±0.1 g/cm3(Predicted) | | form | Solid | | pka | 9.82±0.15(Predicted) | | color | White to off-white | | Sequence | Sar-Arg-Val-Tyr-Val-His-NH2 |
| | TRV120055 Usage And Synthesis |
| Uses | Sar-Arg-Val-Tyr-Val-His-NH2 is a Gq-biased agonists, exhibits 10-fold larger molecular efficacies at the AT1R-Gq fusion protein compared with the AT1R-βarr2 fusion protein[1]. | | References | [1] Rajagopal S, et, al. Quantifying ligand bias at seven-transmembrane receptors. Mol Pharmacol. 2011 Sep;80(3):367-77. DOI:10.1124/mol.111.072801
[2] Strachan RT, et, al. Divergent transducer-specific molecular efficacies generate biased agonism at a G protein-coupled receptor (GPCR). J Biol Chem. 2014 May 16; 289(20): 14211-24. DOI:10.1074/jbc.M114.548131 |
| | TRV120055 Preparation Products And Raw materials |
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