AI 77B manufacturers
- AI 77B
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- $473.00
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2026-07-27
- CAS:77674-99-8
- Purity:
- Supply Ability: 10g
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| Product Name: | AI 77B | | Synonyms: | AI 77B;(3S,4S,5S)-3-Amino-4,5-dihydroxy-6-oxo-6-[[(1S)-1-[(3S)-1-oxo-8-hydroxy-3,4-dihydro-1H-2-benzopyran-3-yl]-3-methylbutyl]amino]hexanoic acid;(3S,4S,5S)-3-Amino-4,5-dihydroxy-6-oxo-6-[[(S)-1-[(S)-3,4-dihydro-8-hydroxy-1-oxo-1H-2-benzopyran-3-yl]-3-methylbutyl]amino]hexanoic acid;D-ribo-Hexonic acid, 3-amino-2,3,6-trideoxy-6-[[(1S)-1-[(3S)-3,4-dihydro-8-hydroxy-1-oxo-1H-2-benzopyran-3-yl]-3-methylbutyl]amino]-6-oxo- | | CAS: | 77674-99-8 | | MF: | C20H28N2O8 | | MW: | 424.44 | | EINECS: | | | Product Categories: | | | Mol File: | 77674-99-8.mol |  |
| | AI 77B Chemical Properties |
| Melting point | 137-138 °C | | Boiling point | 830.3±65.0 °C(Predicted) | | density | 1.381±0.06 g/cm3(Predicted) | | solubility | DMSO: soluble
Methanol: soluble | | pka | 3.48±0.10(Predicted) |
| | AI 77B Usage And Synthesis |
| Description | AI 77B is a pseudopeptide microbial agent with gastroprotective action. | | Uses | Amicoumacin B can be produced by actinomycete, strain 04-5195T.. Amicoumacin B increases the expression of bone morphogenetic protein 2 (BMP-2). Amicoumacin B has inhibitory effect against C. violaceum (MIC = 250 μg/mL). Amicoumacin B has quorum sensing inhibitory activity, and reduces the expression of the C. violaceum operons vioA, vioB, vioD, and vioE, but increases the expression of vioC[1][2]. | | References | [1] Shi WP, et al. Amicoumacins from a desert bacterium: quorum sensing inhibitor against Chromobacterium violaceum. Nat Prod Res. 2021 Dec;35(23):5508-5512. DOI:10.1080/14786419.2020.1788554
[2] Sun W, et al. Nocardia jinanensis sp. nov., an amicoumacin B-producing actinomycete. Int J Syst Evol Microbiol. 2009 Feb;59(Pt 2):417-20. DOI:10.1099/ijs.0.002899-0
[3] De Souza, F.I., Zumiotti, A.V., and Da Silva, C.F. Neuregulins 1-α and 1-β on the regeneration the peripheral nerves[J]. Acta Ortop Bras. |
| | AI 77B Preparation Products And Raw materials |
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