Benzeneacetamide, N-(5-cyclopropyl-1H-pyrazol-3-yl)-α-methyl-4-(2-oxo-1-pyrrolidinyl)-, (αS)-

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Benzeneacetamide, N-(5-cyclopropyl-1H-pyrazol-3-yl)-α-methyl-4-(2-oxo-1-pyrrolidinyl)-, (αS)- Suppliers list
Company Name: Shanghai Chaolan Chemical Technology Center  
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Company Name: TargetMol Chemicals Inc.  
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Benzeneacetamide, N-(5-cyclopropyl-1H-pyrazol-3-yl)-α-methyl-4-(2-oxo-1-pyrrolidinyl)-, (αS)- Basic information
Product Name:Benzeneacetamide, N-(5-cyclopropyl-1H-pyrazol-3-yl)-α-methyl-4-(2-oxo-1-pyrrolidinyl)-, (αS)-
Synonyms:Benzeneacetamide, N-(5-cyclopropyl-1H-pyrazol-3-yl)-α-methyl-4-(2-oxo-1-pyrrolidinyl)-, (αS)-;(S)-PHA533533
CAS:437982-89-3
MF:C19H22N4O2
MW:338.4
EINECS:
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Mol File:437982-89-3.mol
Benzeneacetamide, N-(5-cyclopropyl-1H-pyrazol-3-yl)-α-methyl-4-(2-oxo-1-pyrrolidinyl)-, (αS)- Structure
Benzeneacetamide, N-(5-cyclopropyl-1H-pyrazol-3-yl)-α-methyl-4-(2-oxo-1-pyrrolidinyl)-, (αS)- Chemical Properties
Boiling point 722.6±60.0 °C(predicted)
density 1.348±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
pka13.43±0.10(predicted)
Safety Information
MSDS Information
Benzeneacetamide, N-(5-cyclopropyl-1H-pyrazol-3-yl)-α-methyl-4-(2-oxo-1-pyrrolidinyl)-, (αS)- Usage And Synthesis
Uses(S)-PHA533533 is a cyclin-dependent kinase 2 (CDK2) inhibitor. (S)-PHA533533 shows anti-tumor activity and can induce widespread neuronal UBE3A expression in angelman syndrome model mice[1].
References[1] Vihma H, et al. Ube3a unsilencer for the potential treatment of Angelman syndrome. Nat Commun. 2024 Jul 8;15(1):5558. DOI:10.1038/s41467-024-49788-8
Benzeneacetamide, N-(5-cyclopropyl-1H-pyrazol-3-yl)-α-methyl-4-(2-oxo-1-pyrrolidinyl)-, (αS)- Preparation Products And Raw materials
Tag:Benzeneacetamide, N-(5-cyclopropyl-1H-pyrazol-3-yl)-α-methyl-4-(2-oxo-1-pyrrolidinyl)-, (αS)-(437982-89-3) Related Product Information
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