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| | 2-Thiophenecarboxylic acid hydrazide Basic information |
| | 2-Thiophenecarboxylic acid hydrazide Chemical Properties |
| Melting point | 136-139 °C(lit.) | | density | 1.291 (estimate) | | refractive index | 1.6430 (estimate) | | storage temp. | Keep in dark place,Inert atmosphere,2-8°C | | form | Crystalline Powder | | pka | 12.43±0.10(Predicted) | | color | Slightly yellow to beige | | BRN | 114437 | | InChI | 1S/C5H6N2OS/c6-7-5(8)4-2-1-3-9-4/h1-3H,6H2,(H,7,8) | | InChIKey | SOGBOGBTIKMGFS-UHFFFAOYSA-N | | SMILES | NNC(=O)c1cccs1 | | CAS DataBase Reference | 2361-27-5(CAS DataBase Reference) | | NIST Chemistry Reference | 2-Thiophenecarboxylic acid, hydrazide(2361-27-5) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36-24/25 | | WGK Germany | 3 | | Hazard Note | Irritant | | HS Code | 29349990 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| | 2-Thiophenecarboxylic acid hydrazide Usage And Synthesis |
| Chemical Properties | white to light yellow crystal powder | | Uses | 2-Thiophenecarboxylic acid hydrazide features a planar molecular structure with cis-oriented torsion angles of less than 10° and serves as a ligand for transition metal complexes involving manganese, cobalt, nickel, copper, zinc, cadmium, palladium, and ruthenium[1]. The compound reacts with isatin in ethanol under reflux to synthesize 2-thiophenecarbonylhydrazone-3-isatin[2]. | | Synthesis | 2-Thiophenecarboxylic acid hydrazide is synthesized from 2-thiophenecarboxylic acid derivatives via DCCI activation and subsequent hydrazinolysis, yielding the product at 87%[1]. | | References | [1]Elshaarawy, R. F. M., & Janiak, C. (2011). 2-Thiophenecarbohydrazides: A Novel Efficient Method for the Synthesis of 2-Thiophenecarbohydrazide. Zeitschrift für Naturforschung B, 66(12), 1202–1208. https://doi.org/10.1515/znb-2011-1202
[2]Fahmi, M. R. G., Khumaidah, L., Ilmiah, T. K., Fadlan, A., & Santoso, M. (2018). 2-Thiophenecarboxylic acid hydrazide Derivatives: Synthesis and Anti-Tuberculosis Studies. IOP Conference Series: Materials Science and Engineering, 349, 012039. https://doi.org/10.1088/1757-899x/349/1/012039 |
| | 2-Thiophenecarboxylic acid hydrazide Preparation Products And Raw materials |
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