- Gymnestrogenin
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- $0.00 / 5mg
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2023-02-24
- CAS:19942-02-0
- Min. Order: 5mg
- Purity: ≥98%(HPLC)
- Supply Ability: 10 g
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| | Olean-12-ene-3β,16β,21β,23,28-pentol Basic information |
| Product Name: | Olean-12-ene-3β,16β,21β,23,28-pentol | | Synonyms: | Gymnestrogenin;Olean-12-ene-3β,16β,21β,23,28-pentol;(3beta,4alpha,16beta,21beta)-Olean-12-ene-3,16,21,23,28-pentol;Olean-12-ene-3beta,16beta,21beta,23,28-pentol;Olean-12-ene-3,16,21,23,28-pentol, (3β,4α,16β,21β)- | | CAS: | 19942-02-0 | | MF: | C30H50O5 | | MW: | 490.71 | | EINECS: | | | Product Categories: | | | Mol File: | 19942-02-0.mol |  |
| | Olean-12-ene-3β,16β,21β,23,28-pentol Chemical Properties |
| Melting point | 288-289℃ | | form | Solid | | color | White to off-white |
| | Olean-12-ene-3β,16β,21β,23,28-pentol Usage And Synthesis |
| Uses | Gymnestrogenin is a pentahydroxytriterpene from the leaves of Gymnema sylvestre R.Br[1]. Gymnestrogenin is a LXR antagonist with IC50s of 2.5 and 1.4 μM for LXRα and LXRβ transactivation, respectively. Gymnestrogenin reduces the transcriptional activity of LXR even on its own promoter, thus reducing the mRNA expression[2]. | | References | [1] Stcklin W, et al. [Gymnestrogenin, a new pentahydroxytriterpene from the leaves of Gymnema sylvestre R.Br]. Helv Chim Acta. 1968;51(6):1235-42. DOI:10.1002/hlca.19680510606
[2] Renga B, et al. Molecular decodification of gymnemic acids from Gymnema sylvestre. Discovery of a new class of liver X receptor antagonists. Steroids. 2015 Apr;96:121-31. DOI:10.1016/j.steroids.2015.01.024 |
| | Olean-12-ene-3β,16β,21β,23,28-pentol Preparation Products And Raw materials |
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