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| | 3-BROMO-5-CHLOROPHENYLAMINE Basic information |
| Product Name: | 3-BROMO-5-CHLOROPHENYLAMINE | | Synonyms: | 3-BROMO-5-CHLOROPHENYLAMINE;3-Bromo-5-chloroaniline;3-BROMO-5-CHLOROPHENYLAMINE, 95+%;3-BROMO-5-CHLOROPHEN;3-broMo-5-chlorobenzenaMine;BenzenaMine,3-broMo-5-chloro-;3-Bromo-5-chloroanilin | | CAS: | 96558-78-0 | | MF: | C6H5BrClN | | MW: | 206.47 | | EINECS: | | | Product Categories: | | | Mol File: | 96558-78-0.mol |  |
| | 3-BROMO-5-CHLOROPHENYLAMINE Chemical Properties |
| Melting point | 41-45° | | Boiling point | 284.1±20.0 °C(Predicted) | | density | 1.722±0.06 g/cm3(Predicted) | | storage temp. | Keep in dark place,Inert atmosphere,Room temperature | | form | solid | | pka | 2.47±0.10(Predicted) | | color | Light brown to brown | | InChI | InChI=1S/C6H5BrClN/c7-4-1-5(8)3-6(9)2-4/h1-3H,9H2 | | InChIKey | YYBRLVWWPRAQDX-UHFFFAOYSA-N | | SMILES | C1(N)=CC(Cl)=CC(Br)=C1 |
| Hazard Codes | Xi | | RIDADR | 2018 | | HazardClass | IRRITANT | | PackingGroup | Ⅲ | | HS Code | 2921420090 |
| | 3-BROMO-5-CHLOROPHENYLAMINE Usage And Synthesis |
| Uses | 3-Bromo-5-chloroaniline is a reactant in the preparation of triazolophthalazines as inhibitors of diverse bromodomains | | Synthesis | 2. 5kg 3,4,5_trifluorophenol crude, of which toluene content is 2%, the content of near-boiling impurity 3,5_difluorophenol is 0. 05%, 3,4-difluorophenol content is 0. 03%, 2,4-difluorophenol content is 0. 025%, 2,3,5-trifluorophenol content is 0. 07%, 2, 3,4-trifluorophenol content is 0. 042%, 2,4,6-trifluorophenol content is 0. 01%. The content of 2,3,4-trifluorophenol was 0. 042%, 2,4,6-trifluorophenol was 0. 01 %, and the content of 3,4,5-trifluorophenol was 97.8%. The crude material was put into a 5L distillation kettle, and p-tert-butyltoluene was added 1.5kgo to 100mmHg full reflux Ihr, and then p-tert-butyltoluene fraction was collected from the top of the tower at a reflux ratio of 1 1. After the collection, the tower kettle sampling GC analysis, toluene content is not detected, 3,5- difluorophenol contains 50ppm, 3,4- difluorophenol 62ppm, 2,4- difluorophenol 2ppm, 2,3,5-trifluorophenol 3ppm, 2,3,4-trifluorophenol 2ppm, will be evaporated from the top of the tower to get the high-purity 3,4,5-trifluorophenol weighing 2.2kg, content of 99.98%, distillation yield of 99.9%, distillation yield of 1:1 reflux ratio. . 98 %, and the distillation yield was 89. 97 %. |
| | 3-BROMO-5-CHLOROPHENYLAMINE Preparation Products And Raw materials |
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