- VU 0365114
-
- $53.00
-
2026-04-22
- CAS:1208222-39-2
- Purity: 99.86%
- Supply Ability: 10g
- VU 0365114
-
- $53.00
-
2026-04-22
- CAS:1208222-39-2
- Purity: 99.86%
- Supply Ability: 10g
|
| | VU 0365114 Basic information |
| Product Name: | VU 0365114 | | Synonyms: | VU 0365114;1-Biphenyl-4-ylmethyl-5-trifluoromethoxy-1H-indole-2,3-dione;1-[(1,1'-Biphenyl)-4-ylmethyl]-5-(trifluoromethoxy)-1H-indole-2,3-dione;1H-Indole-2,3-dione, 1-([1,1'-biphenyl]-4-ylmethyl)-5-(trifluoromethoxy)-;VU 0365114,inhibit,Muscarinic acetylcholine receptor,VU0365114,Inhibitor,VU-0365114,mAChR;1-([1,1'-Biphenyl]-4-ylmethyl)-5-(trifluoromethoxy)indoline-2,3-dione;VU 0365114, 10 mM in DMSO;1-([1,1'-Biphenyl]-4-ylmethyl)-5-(trifluoromethoxy)indoline-2,3-dione | | CAS: | 1208222-39-2 | | MF: | C22H14F3NO3 | | MW: | 397.35 | | EINECS: | | | Product Categories: | Intermediates & Fine Chemicals;Heterocycles;Aromatics;Amines;Pharmaceuticals | | Mol File: | 1208222-39-2.mol |  |
| | VU 0365114 Chemical Properties |
| Boiling point | 526.2±60.0 °C(Predicted) | | density | 1.386±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | Ethanol:10.0(Max Conc. mg/mL);25.17(Max Conc. mM)
DMSO:30.0(Max Conc. mg/mL);75.5(Max Conc. mM)
DMF:30.0(Max Conc. mg/mL);75.5(Max Conc. mM) | | form | Powder | | pka | -3.71±0.20(Predicted) | | color | Light yellow to orange |
| | VU 0365114 Usage And Synthesis |
| Uses | VU 0365114 is a selective positive allosteric modulator of M5 (EC50 values are 2.7 μM for human M5, and >30 μM for M1, M2, M3 and M4 receptors). | | Definition | ChEBI: 1-[(4-phenylphenyl)methyl]-5-(trifluoromethoxy)indole-2,3-dione is a member of biphenyls. | | IC 50 | mAChR5 | | storage | Store at RT |
| | VU 0365114 Preparation Products And Raw materials |
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