| Company Name: |
Sigma-Aldrich |
| Tel: |
021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
|
| | Bromophos-ethyl Basic information |
| | Bromophos-ethyl Chemical Properties |
| Boiling point | 122.5°C | | density | 1.590 | | refractive index | n20/D 1.565 | | Fp | 100 °C | | storage temp. | 0-6°C | | solubility | Chloroform (Slightly), Methanol (Slightly) | | Specific Gravity | 1.54 (20℃) | | Water Solubility | 0.34mg/L(20 ºC) | | BRN | 2294153 | | Henry's Law Constant | 6.2×10-1 mol/(m3Pa) at 25℃, HSDB (2015) | | Major Application | agriculture
environmental | | InChI | 1S/C10H12BrCl2O3PS/c1-3-14-17(18,15-4-2)16-10-6-8(12)7(11)5-9(10)13/h5-6H,3-4H2,1-2H3 | | InChIKey | KWGUFOITWDSNQY-UHFFFAOYSA-N | | SMILES | CCOP(=S)(OCC)Oc1cc(Cl)c(Br)cc1Cl | | EPA Substance Registry System | Bromophos-ethyl (4824-78-6) |
| Hazard Codes | T,N | | Risk Statements | 21-25-50/53 | | Safety Statements | 28-36/37-45-60-61 | | RIDADR | 3018 | | WGK Germany | 3 | | RTECS | TE7000000 | | HazardClass | 6.1(a) | | PackingGroup | II | | HS Code | 29201900 | | Storage Class | 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects | | Hazard Classifications | Acute Tox. 3 Dermal
Acute Tox. 3 Oral
Aquatic Acute 1
Aquatic Chronic 1 | | Hazardous Substances Data | 4824-78-6(Hazardous Substances Data) |
| | Bromophos-ethyl Usage And Synthesis |
| Description | Bromophos-ethyl is an obsolete organophosphate insecticide. It has a low aqueous solubility and is quite volatile. It is not generally persistent in soil systems. It is highly toxic to honeybees and aquatic invertebrates but slightly less so to most other species. Bromophos-ethyl is moderately toxic to mammals if ingested and may be an acetyl-cholinesterase inhibitor. | | Uses | Bromophos-ethyl may be used as a reference standard for the determination of the insecticidel in fortified crop and water samples using enzyme-linked immunosorbent assay (ELISA). | | Definition | ChEBI: Bromophos-ethyl is an organic thiophosphate. | | Production Methods | The commercial production of bromophos ethyl, involves synthesising the compound O,O-diethyl O-(2,5-dichloro-4-bromophenyl) thiophosphate through a controlled esterification process. It begins with the halogenation of phenol to produce 2,5-dichloro-4-bromophenol, which serves as the aromatic base. This intermediate is then reacted with diethyl phosphorochloridothioate in the presence of a base such as pyridine or triethylamine, facilitating the formation of the thiophosphate ester linkage. The reaction is typically carried out under anhydrous conditions to prevent hydrolysis and ensure high yield and purity. | | General Description | Bromophos-ethyl is an organophosphorus insecticide used for controlling a wide variety of insects via inhibition of acetylcholinesterase activity. | | Mechanism of action | Non-systemic. Broad-spectrum with contact and stomach action. Acetylcholinesterase (AchE) inhibitor. | | Safety Profile | Poison by ingestion.
Moderately toxic by skin contact and
inhalation. An insecticide. When heated to
decomposition it emits very toxic fumes of
Br-, POx, SOx, and Cl-. See also
CHLOROPHENOLS. | | Pesticide Type | Insecticide |
| | Bromophos-ethyl Preparation Products And Raw materials |
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