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| | Bromo-PEG2-phosphonic acid ethyl ester Basic information |
| Product Name: | Bromo-PEG2-phosphonic acid ethyl ester | | Synonyms: | Bromo-PEG2-phosphonic acid ethyl ester;Bromo-PEG2-phosphonic acid diethyl ester;Phosphonic acid, P-[2-[2-(2-bromoethoxy)ethoxy]ethyl]-, diethyl ester;Diethyl P-[2-[2-(2-bromoethoxy)ethoxy]ethyl]phosphonate;Diethyl [2-[2-(2-Bromoethoxy)ethoxy]ethyl]phosphonate | | CAS: | 1226767-94-7 | | MF: | C10H22BrO5P | | MW: | 333.16 | | EINECS: | | | Product Categories: | | | Mol File: | 1226767-94-7.mol |  |
| | Bromo-PEG2-phosphonic acid ethyl ester Chemical Properties |
| Boiling point | 387.4±27.0 °C(Predicted) | | density | 1.299±0.06 g/cm3(Predicted) | | storage temp. | Storage temp. 2-8°C | | form | Liquid | | color | Colorless to light yellow |
| | Bromo-PEG2-phosphonic acid ethyl ester Usage And Synthesis |
| Description | Bromo-PEG2-phosphonic acid diethyl ester is a PEG linker containing a bromine group and a phosphonic acid diethyl ester. The bromine group is a good leaving group and participates in substitution reactions. The hydrophilic PEG linkers increase the water solubility of the compound in aqueous media. | | Uses | Bromo-PEG2-phosphonic acid diethyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | | IC 50 | PEGs | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | Bromo-PEG2-phosphonic acid ethyl ester Preparation Products And Raw materials |
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