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T&W GROUP |
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- N3-PEG5-Br
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-
2026-07-24
- CAS:1402411-90-8
- Min. Order: 1g
- Purity: 98%
- Supply Ability: 1g/bottle, 10g/bottle, 100g/bottle
- Azido-PEG5-Br
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-
2025-06-07
- CAS:1402411-90-8
- Min. Order: 1g
- Purity: >98.00%
- Supply Ability: 1g
- Bromo-PEG5-Azide
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- $1.00
-
2019-12-23
- CAS:1402411-90-8
- Min. Order: 1KG
- Purity: 97%-99.9%
- Supply Ability: 100kg
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| | Bromo-PEG5-Azide Basic information |
| Product Name: | Bromo-PEG5-Azide | | Synonyms: | Azido-PEG5-Br;Bromo-PEG5-Azide;Br-PEG5-N3;N3-PEG5-CH2CH2Br;N3-PEG5-CH2CH2Br/3,6,9,12,15-Pentaoxaheptadecane, 1-azido-17-bromo-;1-Azido-17-bromo-3,6,9,12,15-pentaoxaheptadecane | | CAS: | 1402411-90-8 | | MF: | C12H24BrN3O5 | | MW: | 370.24 | | EINECS: | | | Product Categories: | peg | | Mol File: | 1402411-90-8.mol |  |
| | Bromo-PEG5-Azide Chemical Properties |
| storage temp. | -20°C, protect from light, stored under nitrogen | | form | Liquid | | color | Colorless to light yellow |
| | Bromo-PEG5-Azide Usage And Synthesis |
| Description | Bromo-PEG5-azide contain a bromide group and a terminal azide. The bromide (Br) is a very good leaving group for nucleophilic reactions. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. PEG5 spacer increases solubility in aqueous media. | | Uses | Bromo-PEG6-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Bromo-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | | IC 50 | PEGs | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | Bromo-PEG5-Azide Preparation Products And Raw materials |
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