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- 3-oxo-1-phenyl-2,7,10,13,16,19,22,25,28-nonaoxa-4-azahentriacontan-31-oic acid
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2026-07-24
- CAS:1334177-87-5
- Min. Order: 1g
- Purity: 98%
- Supply Ability: 1g/bottle, 10g/bottle, 100g/bottle
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| | Cbz-N-amido-PEG8-acid Basic information |
| Product Name: | Cbz-N-amido-PEG8-acid | | Synonyms: | Cbz-N-amido-PEG8-acid;CBZ-NH-PEG8-propionic acid;CBZ-NH-PEG8-CH2CH2COOH;CBZ-N-AMIDO-PEG8-COOH;CBZ-NH-PEG8-COOH;Cbz-NH-PEG8-C2-acid;5,8,11,14,17,20,23,26-Octaoxa-2-azanonacosanedioic acid, 1-(phenylmethyl) ester;CBZ-NH-PEG8-acid | | CAS: | 1334177-87-5 | | MF: | C27H45NO12 | | MW: | 575.65 | | EINECS: | | | Product Categories: | | | Mol File: | 1334177-87-5.mol |  |
| | Cbz-N-amido-PEG8-acid Chemical Properties |
| Boiling point | 681.2±55.0 °C(Predicted) | | density | 1.165±0.06 g/cm3(Predicted) | | storage temp. | Storage temp. 2-8°C | | solubility | Soluble in Water, DMSO, DCM, DMF | | pka | 4.28±0.10(Predicted) | | form | Liquid | | color | Colorless to light yellow |
| | Cbz-N-amido-PEG8-acid Usage And Synthesis |
| Description | Cbz-N-amido-PEG8-acid is a PEG linker containing a CBZ-protected amino group and a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media. The protected amine can be deprotected by acidic conditions. | | Uses | Cbz-NH-PEG8-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | | IC 50 | PEGs; Alkyl/ether | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | Cbz-N-amido-PEG8-acid Preparation Products And Raw materials |
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