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| | 2,6-Dichlorophenylhydrazine hydrochloride Basic information |
| Product Name: | 2,6-Dichlorophenylhydrazine hydrochloride | | Synonyms: | 2,6-Dichoropheynylhydrazine hydrochloride;Hydrazine, (2,6-dichlorophenyl)-, monohydrochloride;6-Dichlorophenylhydrazine hydrochloride;(2,6-dichlorophenyl)hydrazine monohydrochloride;2,6-Dichlorophenylhydrazine hydrochloride, 98+%;2,6-DICHLOROPHENYLHYDRAZINE HCL;2,6-DICHLOROPHENYLHYDRAZINE HYDROCHLORIDE;1,3-Dichloro-2-hydrazinobenzene | | CAS: | 50709-36-9 | | MF: | C6H7Cl3N2 | | MW: | 213.49 | | EINECS: | 256-730-7 | | Product Categories: | Building Blocks;Chemical Synthesis;Nitrogen Compounds;Organic Building Blocks;Hydrazines;Nitrogen Compounds;Organic Building Blocks;Aromatic Hydrazides, Hydrazines, Hydrazones and Oximes;API intermediates | | Mol File: | 50709-36-9.mol |  |
| | 2,6-Dichlorophenylhydrazine hydrochloride Chemical Properties |
| Melting point | 225 °C (dec.)(lit.) | | Boiling point | 346.49°C (rough estimate) | | density | 1.6100 (rough estimate) | | refractive index | 1.6000 (estimate) | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | form | powder to crystal | | color | White to Light yellow to Light orange | | BRN | 4569738 | | InChI | 1S/C6H6Cl2N2.ClH/c7-4-2-1-3-5(8)6(4)10-9;/h1-3,10H,9H2;1H | | InChIKey | CQNIYLLTIOPFCJ-UHFFFAOYSA-N | | SMILES | Cl.NNc1c(Cl)cccc1Cl | | CAS DataBase Reference | 50709-36-9(CAS DataBase Reference) |
| Hazard Codes | T,Xi,Xn | | Risk Statements | 20/21-25-36/37/38-20/21/22 | | Safety Statements | 26-36/37/39-45-22 | | RIDADR | UN 2811 6.1/PG 3 | | WGK Germany | 3 | | Hazard Note | Irritant | | HazardClass | 6.1 | | PackingGroup | Ⅲ | | HS Code | 29280000 | | Storage Class | 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects | | Hazard Classifications | Acute Tox. 3 Oral
Acute Tox. 4 Dermal
Acute Tox. 4 Inhalation
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| | 2,6-Dichlorophenylhydrazine hydrochloride Usage And Synthesis |
| Chemical Properties | white to light yellow powder | | Uses | (2,6-Dichlorophenyl)hydrazine Hydrochloride | | Uses | 2,6-Dichlorophenylhydrazine hydrochloride was used in the preparation of 1-(2,6-dichlorophenyl)-4-methyl-5-(4-methoxyphenyl)-1H-pyrazole-3-carboxylic acid, ethyl ester. | | Synthesis | General procedure for the synthesis of 2,6-dichlorophenylhydrazine hydrochloride from 2,6-dichloroaniline: 2,6-dichloroaniline (10.0 g, 61.72 mmol) was dissolved in an appropriate amount of solvent and cooled to -15 °C. At this temperature, aqueous sodium nitrite (5.11 g, 74.00 mmol) and hydrochloric acid were slowly added. The reaction mixture was stirred at 0-10°C for 15 minutes. The reaction mixture was filtered to remove insoluble matter and subsequently concentrated hydrochloric acid (34.7 g, 150 mmol) was added to the filtrate. The reaction system was maintained at -15 °C and stirring was continued for 30 min, after which the precipitate was collected by filtration to afford 15.00 g of the target product 2,6-dichlorophenylhydrazine hydrochloride. The product was characterized by 1H NMR (300 MHz, DMSO-d6): δ 7.18-7.28 (m, 1H), 7.39-7.52 (m, 2H), 10.30 (br s, 3H); the mass spectrum (MS) showed m/z: 176.90 (M)+. | | References | [1] Patent: WO2013/186692, 2013, A1. Location in patent: Page/Page column 103; 104 |
| | 2,6-Dichlorophenylhydrazine hydrochloride Preparation Products And Raw materials |
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