| Company Name: |
Energy Chemical |
| Tel: |
021-58432009 400-005-6266 |
| Email: |
marketing@energy-chemical.com |
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| | ILICICOLIN F Basic information |
| Product Name: | ILICICOLIN F | | Synonyms: | ILICICOLIN F;LL-Z 1272Z;3-Chloro-4,6-dihydroxy-2-methyl-5-[(2E,4E)-3-methyl-5-[(1S)-5α-acetoxy-1β,2β,6β-trimethyl-3-oxocyclohexyl]-2,4-pentadienyl]benzaldehyde;5-Chloro-2,4-dihydroxy-6-methyl-3-[(2E,4E)-5-[(1S)-3β-acetoxy-1,2α,6α-trimethyl-5-oxocyclohexyl]-3-methyl-2,4-pentadienyl]benzaldehyde;8'-Acetoxyascochlorin;Acetoxy-ascochlorin;Benzaldehyde, 3-[(2E,4E)-5-[(1S,2S,3S,6R)-3-(acetyloxy)-1,2,6-trimethyl-5-oxocyclohexyl]-3-methyl-2,4-pentadien-1-yl]-5-chloro-2,4-dihydroxy-6-methyl;Ilicicolin F >=98% (HPLC), from Verticillium hemipterigenum | | CAS: | 22738-98-3 | | MF: | C25H31ClO6 | | MW: | 462.96 | | EINECS: | | | Product Categories: | Antibiotic | | Mol File: | 22738-98-3.mol |  |
| | ILICICOLIN F Chemical Properties |
| Boiling point | 597.6±50.0 °C(Predicted) | | density | 1.24±0.1 g/cm3(Predicted) | | storage temp. | -20°C | | solubility | DMSO: ≥10mg/mL | | form | solid | | pka | 6.26±0.50(Predicted) |
| WGK Germany | 3 | | HS Code | 2941900000 |
| | ILICICOLIN F Usage And Synthesis |
| Uses | Ilicicolin F is a fungal metabolite that has been found in Fusarium and has diverse biological activities. It inhibits T. vivax alternative oxidase and the E. coli ubiquinol oxidase cytochrome bo (IC50s=0.43 and 0.37 μM, respectively) but not the E. coli ubiquinol oxidase cytochrome bd (IC50=85 μM).2 Ilicicolin F is active against the fungi A. fumigatus and C. albicans (MICs=1.66-3.33 and 6.66-13.33 μg/mL, respectively). It is cytotoxic to HeLa cells with an EC50 value of 0.003 μg/mL. | | References | [1] Ellestad, et al. Some new terpenoid metabolites from an unidentified fusarium species. Tetrahedron 25(6), 1323-1334 (1969). |
| | ILICICOLIN F Preparation Products And Raw materials |
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