- Fmoc-Aib-OH
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2026-09-14
- CAS:94744-50-0
- Min. Order: 1kg
- Purity: 98%
- Supply Ability: 1T
- Fmoc-Aib-OH
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- $1.00
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2020-01-06
- CAS:94744-50-0
- Min. Order: 1g
- Purity: 98%
- Supply Ability: 100KG
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| | Fmoc-Aib-OH Basic information |
| | Fmoc-Aib-OH Chemical Properties |
| Melting point | 182-188 °C | | Boiling point | 544.3±33.0 °C(Predicted) | | density | 1.256±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | | form | powder to crystal | | pka | 3.98±0.10(Predicted) | | color | White to Almost white | | Sensitive | Moisture Sensitive | | BRN | 5604328 | | Major Application | peptide synthesis | | InChI | InChI=1S/C19H19NO4/c1-19(2,17(21)22)20-18(23)24-11-16-14-9-5-3-7-12(14)13-8-4-6-10-15(13)16/h3-10,16H,11H2,1-2H3,(H,20,23)(H,21,22) | | InChIKey | HOZZVEPRYYCBTO-UHFFFAOYSA-N | | SMILES | C(O)(=O)[C@](C)(C)NC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O | | CAS DataBase Reference | 94744-50-0(CAS DataBase Reference) |
| Safety Statements | 22-24/25 | | WGK Germany | 3 | | F | 10-21 | | HazardClass | IRRITANT | | HS Code | 29242990 | | Storage Class | 11 - Combustible Solids |
| | Fmoc-Aib-OH Usage And Synthesis |
| Chemical Properties | Fmoc-Aib-OH is beige powder | | Uses | L-Fmoc-Aminobutyric Acid, is an alanine derivative used in chemical synthesis and peptide chemistry. | | Uses | Fmoc-Aib-OH is used for studying receptor-ligand interactions using encoded amino acid scanning. | | reaction suitability | reaction type: Fmoc solid-phase peptide synthesis | | Synthesis | -Aminoisobutyric acid was added to a round-bottomed flask, 10% aqueous sodium carbonate was added and stirred to dissolve, then dioxane was added, and a 10% dioxane solution of 9-fluorenylmethoxycarbonyl chloride was slowly added dropwise into the reaction solution under an ice bath, and after the dropwise addition was completed the reaction was carried out in an ice bath for 2 hours, then at room temperature for 8 hours, and the reaction was diluted with the addition of water, and the extraction with ether was carried out
4
times, the aqueous layer was placed in an ice bath, the pH was adjusted with concentrated hydrochloric acid until the Congo red paper showed blue, placed in a refrigerator overnight, the white precipitate was extracted with ethyl acetate, the combined organic solution was washed with water, the organic layer was dried with anhydrous magnesium sulfate, and drained to obtain the product Fmoc-2-aminoisobutyric acid. |
| | Fmoc-Aib-OH Preparation Products And Raw materials |
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