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| | 3-CHLORO-4-FLUOROPHENYLMAGNESIUM BROMID& Basic information | | Application |
| | 3-CHLORO-4-FLUOROPHENYLMAGNESIUM BROMID& Chemical Properties |
| Boiling point | 65 °C | | density | 0.966 g/mL at 25 °C | | Fp | 1 °F | | storage temp. | 2-8°C | | InChI | 1S/C6H3ClF.BrH.Mg/c7-5-3-1-2-4-6(5)8;;/h2-4H;1H;/q;;+1/p-1 | | InChIKey | XRNCDMQVKMYTAM-UHFFFAOYSA-M | | SMILES | Fc1ccc([Mg]Br)cc1Cl |
| Hazard Codes | F,C | | Risk Statements | 11-14-19-22-34-40-37 | | Safety Statements | 16-26-36/37/39-45 | | RIDADR | UN 2924 3/PG 2 | | WGK Germany | 1 | | HS Code | 29310099 | | Storage Class | 3 - Flammable liquids | | Hazard Classifications | Acute Tox. 4 Oral Carc. 2 Eye Dam. 1 Flam. Liq. 2 Skin Corr. 1B STOT SE 3 |
| | 3-CHLORO-4-FLUOROPHENYLMAGNESIUM BROMID& Usage And Synthesis |
| Application | Magnesium 3-chloro-4-fluorophenyl bromide can be used as a pharmaceutical synthesis intermediate, such as in the preparation of pyrrolidine derivatives like (2R,5S)-1-(tert-butoxycarbonyl)-5-(3-chloro-4-fluorophenyl)pyrrolidine-2-carboxylic acid ethyl ester. This compound has antagonistic activity against the calcitonin gene-related peptide (CGRP) receptor and can be used to treat various diseases related to the CGRP receptor. | | reaction suitability | reaction type: Grignard Reaction |
| | 3-CHLORO-4-FLUOROPHENYLMAGNESIUM BROMID& Preparation Products And Raw materials |
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