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| | Bis-(2,6-dimethyl-phenyl)-amine Basic information |
| | Bis-(2,6-dimethyl-phenyl)-amine Chemical Properties |
| Melting point | 97-99 °C | | Boiling point | 327.7±11.0 °C(Predicted) | | density | 1.021±0.06 g/cm3(Predicted) | | storage temp. | Keep in dark place,Inert atmosphere,Room temperature | | pka | 0.28±0.50(Predicted) | | Appearance | White to off-white Solid |
| | Bis-(2,6-dimethyl-phenyl)-amine Usage And Synthesis |
| Synthesis | General procedure for the synthesis of bis(2,6-dimethylbenzene)amine from 2,6-dimethylbromobenzene and 2,6-dimethylaniline: in a Schlenk tube equipped with a magnetic stirrer, base (3.0 mmol), PdCl2(Ph3P)2 (3.5 mg, 0.5 mol%), Ph3P (2.6 mg, 1.0 mol%), 2,6- dimethylaniline (1.0 mmol) and 2,6-dimethylbromobenzene (2.5 mmol) in o-xylene (8.0 mL) solution. The reaction mixture was heated to reflux and stirred for 8 hours (or 12 hours) under nitrogen protection. Upon completion of the reaction, the solvent was evaporated under reduced pressure and the residue was purified by fast column chromatography (eluent: petroleum ether/ethyl acetate) to afford the target product, bis(2,6-dimethylphenyl)amine. | | References | [1] Journal of Organic Chemistry, 2013, vol. 78, # 10, p. 4649 - 4664
[2] RSC Advances, 2013, vol. 3, # 12, p. 3840 - 3843
[3] Tetrahedron, 2014, vol. 70, # 32, p. 4754 - 4759 |
| | Bis-(2,6-dimethyl-phenyl)-amine Preparation Products And Raw materials |
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