Benzenesulfonamide, N-[4'-[(3,4-dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)methyl][1,1'-biphenyl]-4-yl]-4-methoxy-N-[(4-methoxyphenyl)sulfonyl]-

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Benzenesulfonamide, N-[4'-[(3,4-dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)methyl][1,1'-biphenyl]-4-yl]-4-methoxy-N-[(4-methoxyphenyl)sulfonyl]- Suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +17819995354
Email: marketing@targetmol.com
Products Intro: Product Name:P-gp inhibitor 4
CAS:2652001-05-1
Package:25mg;1520USD|50mg;1980USD|100mg;2500USD
Company Name: Nantong Hanfang Biotechnology Co. , Ltd.  
Tel: hanfangpharma@126.com; 18616537568
Email: hanfangpharma@126.com
Products Intro: CAS:2652001-05-1
Purity:98% HPLC Package:10mg;1g;10g;100g;1kg
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
Products Intro: Product Name:P-gp inhibitor 4
CAS:2652001-05-1
Package:25mg/RMB 10600;50mg/RMB 13800;100mg/RMB 17500

Benzenesulfonamide, N-[4'-[(3,4-dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)methyl][1,1'-biphenyl]-4-yl]-4-methoxy-N-[(4-methoxyphenyl)sulfonyl]- manufacturers
Benzenesulfonamide, N-[4'-[(3,4-dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)methyl][1,1'-biphenyl]-4-yl]-4-methoxy-N-[(4-methoxyphenyl)sulfonyl]- Basic information
Product Name:Benzenesulfonamide, N-[4'-[(3,4-dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)methyl][1,1'-biphenyl]-4-yl]-4-methoxy-N-[(4-methoxyphenyl)sulfonyl]-
Synonyms:Benzenesulfonamide, N-[4'-[(3,4-dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)methyl][1,1'-biphenyl]-4-yl]-4-methoxy-N-[(4-methoxyphenyl)sulfonyl]-;P-gp inhibitor 4
CAS:2652001-05-1
MF:C38H38N2O8S2
MW:714.85
EINECS:
Product Categories:
Mol File:2652001-05-1.mol
Benzenesulfonamide, N-[4'-[(3,4-dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)methyl][1,1'-biphenyl]-4-yl]-4-methoxy-N-[(4-methoxyphenyl)sulfonyl]- Structure
Benzenesulfonamide, N-[4'-[(3,4-dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)methyl][1,1'-biphenyl]-4-yl]-4-methoxy-N-[(4-methoxyphenyl)sulfonyl]- Chemical Properties
Boiling point 838.3±75.0 °C(Predicted)
density 1.313±0.06 g/cm3(Predicted)
pka6.97±0.20(Predicted)
Safety Information
MSDS Information
Benzenesulfonamide, N-[4'-[(3,4-dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)methyl][1,1'-biphenyl]-4-yl]-4-methoxy-N-[(4-methoxyphenyl)sulfonyl]- Usage And Synthesis
UsesP-gp inhibitor 4 (Compound 8b) is a selective P-glycoprotein modulator with an EC50 of 94 nM. P-gp inhibitor 4 increases agent transport across gastro-intestinal barrier and recovers doxorubicin toxicity in multidrug resistant cancer cells[1].
References[1] Contino M, et al. One molecule two goals: A selective P-glycoprotein modulator increases drug transport across gastro-intestinal barrier and recovers doxorubicin toxicity in multidrug resistant cancer cells. Eur J Med Chem. 2020 Dec 15;208:112843. DOI:10.1016/j.ejmech.2020.112843
Benzenesulfonamide, N-[4'-[(3,4-dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)methyl][1,1'-biphenyl]-4-yl]-4-methoxy-N-[(4-methoxyphenyl)sulfonyl]- Preparation Products And Raw materials
Tag:Benzenesulfonamide, N-[4'-[(3,4-dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)methyl][1,1'-biphenyl]-4-yl]-4-methoxy-N-[(4-methoxyphenyl)sulfonyl]-(2652001-05-1) Related Product Information