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| | excisanin A Basic information |
| Product Name: | excisanin A | | Synonyms: | (14R)-1α,7α,12α,14-Tetrahydroxykaur-16-en-15-one;1α,7α,12α,14β-Tetrahydroxykaura-16-ene-15-one;1alpha,7alpha,12alpha,14beta-Tetrahydroxy-ent-kaur-16-en-15-one;Kaur-16-en-15-one, 1,7,12,14-tetrahydroxy-, (1α,7α,12α,14R)- | | CAS: | 78536-37-5 | | MF: | C20H30O5 | | MW: | 350.45 | | EINECS: | | | Product Categories: | Miscellaneous Natural Products | | Mol File: | 78536-37-5.mol |  |
| | excisanin A Chemical Properties |
| Boiling point | 558.719±50.00 °C(Press: 760.00 Torr)(predicted) | | density | 1.301±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | | pka | 12.784±0.70(predicted) |
| | excisanin A Usage And Synthesis |
| Description | Excisanin A is a diterpenoid compound purified from Isodon macrocalyxin D that has anti-cancer properties with little toxicity. | | Uses | Excisanin A is a potent anticancer agent. Excisanin A inhibits cell proliferation, migration, adhesion and invasion. Excisanin A decreases the expression of MMP-2, MMP-9, p-FAK, p-Src, integrin β1 protein. Excisanin A has the potential for the research of breast cancer[1]. | | References | [1] Qin J, et al. A diterpenoid compound, excisanin A, inhibits the invasive behavior of breast cancer cells by modulating the integrin β1/FAK/PI3K/AKT/β-catenin signaling. Life Sci. 2013 Nov 4;93(18-19):655-63. DOI:10.1016/j.lfs.2013.09.002 |
| | excisanin A Preparation Products And Raw materials |
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