(S)-(-)-3-Benzyloxy-1,2-propanediol

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(S)-(-)-3-Benzyloxy-1,2-propanediol manufacturers

(S)-(-)-3-Benzyloxy-1,2-propanediol Basic information
Product Name:(S)-(-)-3-Benzyloxy-1,2-propanediol
Synonyms:(S)-GLYCEROL 1-BENZYL ETHER;(S)-(-)-GLYCEROL ALPHA-BENZYL ETHER;(S)-(-)-1-BENZYLGLYCEROL;(S)-3-BENZYLOXY-1,2-PROPANEDIOL;1-O-BENZYL-SN-GLYCEROL;1-BENZYL-SN-GLYCEROL;(S)-(-)-Benzylglycerol;(S)-(-)-1-BENZYLGLYCEROL 98%
CAS:17325-85-8
MF:C10H14O3
MW:182.22
EINECS:
Product Categories:Chiral Building Blocks;Simple Alcohols (Chiral);Synthetic Organic Chemistry;Heterocyclic Compounds
Mol File:17325-85-8.mol
(S)-(-)-3-Benzyloxy-1,2-propanediol Structure
(S)-(-)-3-Benzyloxy-1,2-propanediol Chemical Properties
Melting point 24-26 °C(lit.)
Boiling point 261 °C(lit.)
alpha -5.5o (C=20% IN CHLOROFORM)
density 1.0966 (rough estimate)
refractive index -5.5 ° (C=20, CHCl3)
Fp >230 °F
storage temp. Sealed in dry,2-8°C
pka13.65±0.20(Predicted)
form powder to lump to clear liquid
color White or Colorless to Light yellow
Optical Rotation[α]20/D 5.5±0.5°, c = 20% in chloroform
BRN 2415534
CAS DataBase Reference17325-85-8(CAS DataBase Reference)
Safety Information
Safety Statements 22-24/25
WGK Germany 3
3-10
HS Code 2905399590
MSDS Information
ProviderLanguage
SigmaAldrich English
(S)-(-)-3-Benzyloxy-1,2-propanediol Usage And Synthesis
Chemical Propertieswhite to slightly yellow crystalline low melting
Uses(S)-(-)-3-Benzyloxy-1,2-propanediol is a useful building block. It is used in the preparation of the nucleotide analog (S)-1-[3-hydroxy-2-(phosphonylmethoxy)propyl]cystosine with antiviral activities. It is also used to synthesize cationic cardiolipin analogs with drug delivery systems such as transfection reagents.
Purification MethodsPurify the diol by repeated fractional distillation. [Baer et al. J Biol Chem 230 447 1958, Gigg & Gigg J Chem Soc C 1865 1967, Beilstein 6 IV 2247.]
(S)-(-)-3-Benzyloxy-1,2-propanediol Preparation Products And Raw materials
Preparation Products1-O-Benzyl-rac-glycerol
Tag:(S)-(-)-3-Benzyloxy-1,2-propanediol(17325-85-8) Related Product Information
Benzyl ether 3-Benzyloxy-1,2-propanediol 2,3,4,6-Tetra-O-benzoyl-alpha-D-glucopyranosyl bromide alpha-D-Glucopyranose pentabenzoate Glyceryl tribenzoate Methyl 4,6-O-benzylidene-alpha-D-glucopyranoside HAMAMELITANNIN beta-D-Ribofuranose 1-acetate 2,3,5-tribenzoate 5'-O-Dimethoxytrityl-N-benzoyl-desoxycytidine ORIENTIN 5'-O-Dimethoxytrityl-N-isobutyryl-deoxyguanosine HOMOORIENTIN 5'-O-Dimethoxytrityl-deoxythymidine Vitexin Dibenzoyltartaric acid 1,3-Bis(benzyloxy)-2-propanol 1-O-Benzyl-rac-glycerol (R)-(-)-1-Benzyloxy-3-(p-tosyloxy)-2-propanol