2-(4-Chlorophenyl)-3-methylbutyric acid

2-(4-Chlorophenyl)-3-methylbutyric acid Suppliers list

Company Name:	Qingdao Helino Chemical Co. LTD Gold
Tel:	198 6221 1367 18561921626
Email:	hailinuochem@163.com

Company Name:	TCI (Shanghai) Development Co., Ltd.
Tel:	021-67121386
Email:	Sales-CN@TCIchemicals.com

2-(4-Chlorophenyl)-3-methylbutyric acid manufacturers

2-(4-Chlorophenyl)-3-methylbutyric acid Basic information

Product Name:	2-(4-Chlorophenyl)-3-methylbutyric acid
Synonyms:	TIMTEC-BB SBB008321;2-(p-chlorophenyl)-3-methyl-butyricaci;4-chloro-a-(1-methylethyl)benzeneaceticacid;4-chloro-alpha-(1-methylethyl)-benzeneaceticaci;alpha-(p-Chlorophenyl)isovaleric acid;Benzeneacetic acid, 4-chloro-alpha-(1-methylethyl)-;Butyric acid, 2-(p-chlorophenyl)-3-methyl-;FENVALERATE FREE ACID METABOLITE
CAS:	2012-74-0
MF:	C11H13ClO2
MW:	212.67
EINECS:	217-934-1
Product Categories:	C11 to C12;Carbonyl Compounds;Carboxylic Acids
Mol File:	2012-74-0.mol

2-(4-Chlorophenyl)-3-methylbutyric acid Chemical Properties

Melting point	87-91 °C(lit.)
Boiling point	318.7±17.0 °C(Predicted)
density	1.184±0.06 g/cm3(Predicted)
Fp	>230 °F
storage temp.	Sealed in dry,Room Temperature
solubility	Chloroform (slightly), DMSO (Slightly)
form	powder to crystal
pka	4.13±0.10(Predicted)
color	White to Orange to Green
InChI	1S/C11H13ClO2/c1-7(2)10(11(13)14)8-3-5-9(12)6-4-8/h3-7,10H,1-2H3,(H,13,14)
InChIKey	VTJMSIIXXKNIDJ-UHFFFAOYSA-N
SMILES	CC(C)C(C(O)=O)c1ccc(Cl)cc1
CAS DataBase Reference	2012-74-0(CAS DataBase Reference)
EPA Substance Registry System	Benzeneacetic acid, 4-chloro-.alpha.-(1-methylethyl)- (2012-74-0)

Safety Information

MSDS Information

Provider	Language
SigmaAldrich	English

2-(4-Chlorophenyl)-3-methylbutyric acid Usage And Synthesis

Uses	2-(4-Chlorophenyl)-3-methylbutanoic Acid can be used for the multi-residue analysis of organic pollutants in hair and urine for matrices composition.
Definition	ChEBI: A monocarboxylic acid consisting of isovaleric acid having a 4-chlorophenyl group at the 2-position.
Synthesis	1878-66-6 75-29-6 2012-74-0 To a xylene dispersion of fine potassium hydroxide with a particle size of less than 100 μm (26 g, 0.33 mol) prepared by the method of Example 1, 50 ml of a xylene solution of isopropyl chloride (37.5 g, 0.22 mol) was added. The mixed solution was added dropwise in about 10 minutes, followed by a continuous reaction at 70°C to 80°C for 50 minutes. Upon completion of the reaction, the reaction mixture was poured into 300 ml of water and the aqueous and organic layers were separated. The organic layer was concentrated and xylene was removed by distillation and finally subjected to reduced pressure distillation to give 43 g of α-isopropyl-4-chlorophenylacetic acid (91% yield, melting point 88°-89°C).
References	[1] Patent: US4307034, 1981, A

2-(4-Chlorophenyl)-3-methylbutyric acid Preparation Products And Raw materials

Raw materials	4-Chlorotoluene-->2-Bromopropane-->4-Chlorobenzyl chloride-->2-Chloropropane-->4-Chlorobenzyl cyanide-->2-(4-Chlorophenyl)-3-methylbutyronitrile-->4-Chlorophenylacetic acid-->Water-->1,3-Cyclohexadiene, 5,5-dimethyl--->Potassium hydroxide
Preparation Products	Fenvalerate-->2-(p-Hydroxyphenyl)isovaleric acid-->Isopropyl(4-chlorophenyl)acetyl chloride

Tag:2-(4-Chlorophenyl)-3-methylbutyric acid(2012-74-0) Related Product Information

4-Chlorobenzaldehyde Benzeneacetic acid, 4-chloro-α-(1-methylethyl)-, cyano(4-phenoxyphenyl)methyl ester, (R*,S*)- Esfenvalerate free acid metabolite (S)-2-(4'-Chlorophenyl)-2-(2''-oxocyclohexyl)glycolic acid ethyl ester Isovaleric acid 4-Chlorophenylacetic acid Esfenvalerate 2-(4-Chlorophenyl)-3-methylbutyric acid VALERATE Fenvalerate