N-(5,6-Dimethyl-1H-benzimidazol-2-yl)guanidine

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Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
N-(5,6-Dimethyl-1H-benzimidazol-2-yl)guanidine Basic information
Product Name:N-(5,6-Dimethyl-1H-benzimidazol-2-yl)guanidine
Synonyms:TOSLAB-BB TOS-BB-1282;2-(5,6-dimethyl-1H-benzimidazol-2-yl)guanidine;Guanidine, (5,6-dimethyl-1H-benzimidazol-2-yl)- (9CI);DHFR-IN-19;N-(5,6-Dimethyl-1H-benzimidazol-2-yl)guanidine
CAS:41927-06-4
MF:C10H13N5
MW:203.24
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Mol File:41927-06-4.mol
N-(5,6-Dimethyl-1H-benzimidazol-2-yl)guanidine Structure
N-(5,6-Dimethyl-1H-benzimidazol-2-yl)guanidine Chemical Properties
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MSDS Information
N-(5,6-Dimethyl-1H-benzimidazol-2-yl)guanidine Usage And Synthesis
UsesDHFR-IN-19 (Compound 2g) is a selective inhibitor for TbDHFR with Ki of 9 nM. DHFR-IN-19 exhibits antiparasitic activity against Trypanosoma brucei with an EC50 of 14.5 μM[1].
References[1] Francesconi V, et al., Identification of Innovative Folate Inhibitors Leveraging the Amino Dihydrotriazine Motif from Cycloguanil for Their Potential as Anti-Trypanosoma brucei Agents. ACS Infect Dis. 2024 Jul 2. DOI:10.1021/acsinfecdis.4c00113
N-(5,6-Dimethyl-1H-benzimidazol-2-yl)guanidine Preparation Products And Raw materials
Tag:N-(5,6-Dimethyl-1H-benzimidazol-2-yl)guanidine(41927-06-4) Related Product Information
N-(5,6-Dimethyl-1H-benzimidazol-2-yl)guanidine 5-Methyl-1H-benzimidazol-2-amine 2-Guanidinobenzimidazole 2-Aminobenzimidazole 5,6-Dimethylbenzimidazole Guanidine, (5-methyl-1H-benzimidazol-2-yl)- (9CI) 2-Amino-5,6-dimethylbenzimidazole