| Company Name: |
J & K SCIENTIFIC LTD.
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| Tel: |
18210857532; 18210857532 |
| Email: |
jkinfo@jkchemical.com |
| Products Intro: |
Product Name:2-Oleoyl Glycerol (80%)
CAS:3443-84-3
Package:2.5Mg,25Mg
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| Company Name: |
Hangzhou Sage Chemical Co., Ltd.
|
| Tel: |
+86057186818502 13588463833 |
| Email: |
info@sagechem.com |
| Products Intro: |
Product Name:9-Octadecenoic Acid (Z)- , 2-hydroxy-1-(hydroxyMethyl) ethyl ester
CAS:3443-84-3
Purity:98% Package:1g;5g;100g;Bulk
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2-MONOOLEIN manufacturers
- 2-Oleoylglycerol
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- $95.00 / 1mg
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2026-01-05
- CAS:3443-84-3
- Min. Order:
- Purity: 98.00%
- Supply Ability: 10g
- 2-MONOOLEIN
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- $1.00 / 1Kg
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2024-07-25
- CAS:3443-84-3
- Min. Order: 1Kg
- Purity: 98%
- Supply Ability: 20T
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| | 2-MONOOLEIN Basic information |
| | 2-MONOOLEIN Chemical Properties |
| Melting point | 23-23.5 °C | | Boiling point | 485.4±35.0 °C(Predicted) | | density | 0.9963 g/cm3 | | Fp | 113 °C | | storage temp. | −20°C | | solubility | Chloroform (Slightly), Ethyl Acetate (Slightly) | | form | Oil | | pka | 13.54±0.10(Predicted) | | color | Colourless | | Stability: | Temperature Sensitive |
| | 2-MONOOLEIN Usage And Synthesis |
| Chemical Properties | Clear Colourless Oil | | Uses | A metabolite of 2-acylglycerol
Contain up to 20% 1-isomer. | | Uses | A metabolite of 2-acylglycerol used as biomarker. Contain up to 20% 1-isomer. | | Definition | ChEBI: A 2-monoglyceride where the acyl group is (9Z)-octadecenoyl. | | Biological Activity | 2-oleoyl glycerol (2-OG) acts as an agonist for G protein-coupled receptor 119 (GPR119) in vitro and stimulates glucagon-like peptide-1 (GLP-1) secretion in vivo. | | in vivo | 2-Oleoylglycerol (20 μg/mouse in 0.2 mL PBS, i.v., three times a week for 6 weeks) induces liver fibrosis in a non-alcoholic steatohepatitis (NASH) model through promoting TGF-β1 production in liver MΦs[3]. | Animal Model: | C57BL/6 J mice, CL-HFS-induced non-alcoholic steatohepatitis (NASH) model[3] | | Dosage: | 20?μg/mouse in 0.2?mL PBS | | Administration: | Intravenous administration (I.V.), three times a week for 6 weeks | | Result: | Showed increased hepatic infiltration of inflammatory cells, increased collagen and α-SMA production; 2-OG enhanced liver resident MΦ and HSC activation. |
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| | 2-MONOOLEIN Preparation Products And Raw materials |
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