| Company Name: |
Alfa Aesar |
| Tel: |
400-6106006 |
| Email: |
saleschina@alfa-asia.com |
2,6-Dichloropyrimidine-4-carboxylic acid manufacturers
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| | 2,6-Dichloropyrimidine-4-carboxylic acid Basic information |
| Product Name: | 2,6-Dichloropyrimidine-4-carboxylic acid | | Synonyms: | NSC46804;2,6-DICHLORO-PYRIMIDINE-4-CARBOXYLIC ACID;2,4-Dichloropyrimidine-6-carboxylic acid;Methyl 2,6-dichloro-4-pyrimidinecarboxylate;4-PyriMidinecarboxylic acid, 2,6-dichloro-;2,6-DICHLORO-4-PYRIMIDINE CARBOXYLIC ACID;2,6-DichloropyriMidin-4-carboxylic acid;2,6-DICHLORO-4-PYRIMIDINE CARBOXYLIC ACID METHYL ESTER | | CAS: | 16492-28-7 | | MF: | C5H2Cl2N2O2 | | MW: | 192.99 | | EINECS: | | | Product Categories: | | | Mol File: | 16492-28-7.mol |  |
| | 2,6-Dichloropyrimidine-4-carboxylic acid Chemical Properties |
| Melting point | 54-56°C | | Boiling point | 374.9±22.0 °C(Predicted) | | density | 1.718±0.06 g/cm3(Predicted) | | storage temp. | -20°C, stored under nitrogen | | pka | 2.07±0.10(Predicted) | | Appearance | Light yellow to yellow Solid | | Water Solubility | Slightly soluble in water. | | InChI | 1S/C5H2Cl2N2O2/c6-3-1-2(4(10)11)8-5(7)9-3/h1H,(H,10,11) | | InChIKey | MOXUTXQEKYPKKS-UHFFFAOYSA-N | | SMILES | OC(=O)c1cc(Cl)nc(Cl)n1 |
| Hazard Codes | Xi | | Risk Statements | 36/38 | | Safety Statements | 26 | | WGK Germany | 3 | | HazardClass | IRRITANT, KEEP COLD | | HS Code | 29335990 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Eye Irrit. 2
Skin Irrit. 2 |
| | 2,6-Dichloropyrimidine-4-carboxylic acid Usage And Synthesis |
| Uses | 2,6-Dichloropyrimidine-4-carboxylic acid is used as pharmaceutical intermediate. | | General Description |
2,6-Dichloropyrimidine-4-carboxylic acid is a chloropyrimidine compound. Its pyrimidine ring bears two reactive functional groups—chlorine atoms—and a carboxyl group. In the presence of methanol, the chlorine atoms at positions 2 and 6 undergo solvolysis to form hydroxyl groups; hydrolysis in boiling water yields uracil. This substance is highly reactive and can serve as an intermediate in the synthesis of other chloropyrimidines[1].
| | References | [1] Rand, L., Swisher, J. V., Cronin, C. J. (1962). Reactions Catalyzed by Potassium Fluoride. III. The Knoevenagel Reaction. The Journal of Organic Chemistry, 27 10, 3505–3507. https://doi.org/10.1021/jo01057a024 |
| | 2,6-Dichloropyrimidine-4-carboxylic acid Preparation Products And Raw materials |
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