- MX69
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- $56.00 / 5mg
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2026-04-12
- CAS:1005264-47-0
- Min. Order:
- Purity: 99.78%
- Supply Ability: 10g
- MX-69
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- $1.00 / 1g
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2019-12-24
- CAS:1005264-47-0
- Min. Order: 1g
- Purity: 99%
- Supply Ability: 20kg
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| Product Name: | MX-69 | | Synonyms: | MX-69;CS-2402;MX69 (MX 69;Benzoic acid, 4-[8-[[(3,4-dimethylphenyl)amino]sulfonyl]-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolin-4-yl]-;E1/E2/E3 Enzyme,inhibit,E3 ligating enzyme,MX 69,Ubiquitin ligase,IAP,MX69,E1 activating enzyme,E2 conjugating enzyme,Ubiquitin conjugating enzyme,MX-69,Inhibitor,Ubiquitin activating enzyme,MDM-2/p53;4-(8-(N-(3,4-Dimethylphenyl)sulfamoyl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolin-4-yl)benzoic acid;MX69, 10 mM in DMSO;MX69 ，S8403 | | CAS: | 1005264-47-0 | | MF: | C27H26N2O4S | | MW: | 474.57 | | EINECS: | | | Product Categories: | | | Mol File: | 1005264-47-0.mol |  |
| | MX-69 Chemical Properties |
| storage temp. | Store at -20°C | | solubility | DMSO: soluble | | form | A solid | | color | White to off-white |
| | MX-69 Usage And Synthesis |
| Uses | MX69 is an inhibitor of MDM2/XIAP, used for cancer treatment. | | in vivo | MX69-induced MDM2 downregulation results in activation of p53 which contributes to inhibition of cancer cell proliferation in vivo[1]. | | References | [1] Lubing Gu, et al. Discovery of Dual Inhibitors of MDM2 and XIAP for Cancer Treatment. Cancer Cell. 2016 Oct 10;30(4):623-636 DOI:10.1016/j.ccell.2016.08.015
[2] Gu L, et al. Discovery of Dual Inhibitors of MDM2 and XIAP for Cancer Treatment. Cancer Cell. 2016 Oct 10;30(4):623-636 |
| | MX-69 Preparation Products And Raw materials |
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